Affinity DataKi: 0.440nMAssay Description:Inhibition of [3H]-pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of [3H]-pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of [3H]-pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of [3H]-pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of [3H]-pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of [3H]-pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibition of [3H]-pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of [3H]-pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Inhibition of [3H]-pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Inhibition of [3H]-pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of [3H]-pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Inhibition of [3H]-pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of [3H]-pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
Affinity DataKi: 157nMAssay Description:Inhibition of [3H]-pentazocine binding to Sigma opioid receptor type 1More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 0.320nMAssay Description:The FGFR1-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Kyoto 607-8042
Curated by ChEMBL
Kyoto 607-8042
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 0.670nMAssay Description:The FGFR1-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Kyoto 607-8042
Curated by ChEMBL
Kyoto 607-8042
Curated by ChEMBL
Affinity DataIC50: 0.680nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 0.810nMAssay Description:The FGFR1-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2 in cell-intact assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Kyoto 607-8042
Curated by ChEMBL
Kyoto 607-8042
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Kyoto 607-8042
Curated by ChEMBL
Kyoto 607-8042
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 1.20nMAssay Description:The FGFR3-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Kyoto 607-8042
Curated by ChEMBL
Kyoto 607-8042
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells by [14C]AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 minsMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 1.40nMAssay Description:The FGFR1-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 1.40nMAssay Description:The FGFR1-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair