Affinity DataIC50: 0.410nMAssay Description:Displacement of fluormone-labeled ES2 from recombinant full length human ERalpha ligand binding domain expressed in insect cells after 2 hrs by TR-FR...More data for this Ligand-Target Pair
Affinity DataIC50: 0.530nMAssay Description:Displacement of fluormone-labeled ES2 from recombinant full length human ERalpha ligand binding domain expressed in insect cells after 2 hrs by TR-FR...More data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:Inhibition of MMP2 (unknown origin) using Mca-PLGLDpaAR fluorescent substrate incubated for 2 hrs by microplate reader methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of fluormone-labeled ES2 from recombinant full length human ERalpha ligand binding domain expressed in insect cells after 2 hrs by TR-FR...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 2.70nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 2.80nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of fluoromone ligand from recombinant ER-alpha (unknown origin) by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 3.20nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 3.30nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 3.70nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Displacement of fluoromone ligand from recombinant ER-alpha (unknown origin) by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 4.30nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 4.40nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 4.70nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 5nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 5.30nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of MMP2 (unknown origin) using Mca-PLGLDpaAR fluorescent substrate incubated for 2 hrs by microplate reader methodMore data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 6.40nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 6.40nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 6.70nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 6.80nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 6.80nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Downregulation of ER-alpha expression in human T47D cells measured after 5 days by Western blot analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 8.40nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Downregulation of ER-alpha expression in human tamoxifen-resistant T47D cells over-expressing PKC-alpha measured after 5 days by Western blot analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Downregulation of ER-alpha expression in human T47D cells measured after 5 days by Western blot analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 9.5nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 11nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Downregulation of ER-alpha expression in human tamoxifen-resistant T47D cells over-expressing PKC-alpha measured after 5 days by Western blot analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of fluormone-labeled ES2 from recombinant full length human ERalpha ligand binding domain expressed in insect cells after 2 hrs by TR-FR...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 14nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 15nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 15nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 16nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 16nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 19nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 20nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 20nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 20nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of full length human PDE4D7 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 24nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 24nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 24nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 26nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin) autophosphorylation after 1 hrMore data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 32nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 32nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 32nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 32nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 33nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair