TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
National Institute Of Immunology
Curated by ChEMBL
National Institute Of Immunology
Curated by ChEMBL
Affinity DataKi: 0.00190nMAssay Description:Inhibition of Plasmodium falciparum ENR in presence of EGCG by dilution assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.00600nMAssay Description:Inhibition of PDE10A (unknown origin) by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Inhibition of PDE10A (unknown origin) by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Inhibition of PDE10A (unknown origin) by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Inhibition of PDE10A (unknown origin) by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Inhibition of PDE10A (unknown origin) by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Inhibition of PDE10A (unknown origin) by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Inhibition of PDE10A (unknown origin) by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Inhibition of PDE10A (unknown origin) by IMAP assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 0.0417nMAssay Description:Mixed type inhibition of electric eel AChE assessed as inhibition constant using varying levels of acetylthiocholine as substrate by reciprocal Linew...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
National Institute Of Immunology
Curated by ChEMBL
National Institute Of Immunology
Curated by ChEMBL
Affinity DataKi: 0.0521nMAssay Description:Inhibition of Plasmodium falciparum ENR in presence of ECG by dilution assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.100nMAssay Description:Binding affinity to EZH2 (unknown origin)More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
National Institute Of Immunology
Curated by ChEMBL
National Institute Of Immunology
Curated by ChEMBL
Affinity DataKi: 0.109nMAssay Description:Inhibition of Plasmodium falciparum ENR in presence of EGC by dilution assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Inhibition of PDE10A (unknown origin) by IMAP assayMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
National Institute Of Immunology
Curated by ChEMBL
National Institute Of Immunology
Curated by ChEMBL
Affinity DataKi: 0.281nMAssay Description:Inhibition of Plasmodium falciparum ENR in presence of quercetin by dilution assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.282nMAssay Description:Displacement of [125I]I-AB-MEAC from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.282nMAssay Description:Displacement of [125I]I-AB-MEAC from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand co-expressed with delta and kappa opioid receptor...More data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of [125I]I-AB-MEAC from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of [125I]I-AB-MEAC from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [125I]I-AB-MEAC from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [125I]I-AB-MEAC from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of PDE10A (unknown origin) by IMAP assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -55.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -55.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.440nMAssay Description:Inhibition of PDE10A (unknown origin) by IMAP assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand co-expressed with delta and kappa opioid receptor...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
TargetAurora kinase A-interacting protein(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.600nM ΔG°: -54.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.676nMAssay Description:Displacement of [125I]I-AB-MEAC from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.676nMAssay Description:Displacement of [125I]I-AB-MEAC from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -54.4kJ/moleT: 2°CAssay Description:A competitive inhibition binding assay was performed employing Eu-NDP-α-MSH (PerkinElmer Life Sciences catalog No. AD0225) with determination b...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -54.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair