Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Asahi Chemical Industry
Curated by ChEMBL
Asahi Chemical Industry
Curated by ChEMBL
Affinity DataKi: 0.00270nMAssay Description:Binding affinity by measuring displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
Affinity DataKi: 1.74nMAssay Description:Inhibition of rabbit factor 10a by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 2.85nMAssay Description:Inhibition of human factor 10a by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 8.77nMAssay Description:Inhibition of rat factor 10a by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Asahi Chemical Industry
Curated by ChEMBL
Asahi Chemical Industry
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Binding affinity by measuring displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Binding affinity for DA2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Inhibition of human factor 10a by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Asahi Chemical Industry
Curated by ChEMBL
Asahi Chemical Industry
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor by use of [3H]8-OH-DPAT in male ratMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Binding affinity for DA2 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Asahi Chemical Industry
Curated by ChEMBL
Asahi Chemical Industry
Curated by ChEMBL
Affinity DataKi: 280nMAssay Description:Binding affinity of the compound towards 5-hydroxytryptamine 1A receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 2.54E+3nMAssay Description:Inhibition of human thrombin by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+4nMAssay Description:Inhibition of human recombinant tissue plasminogen activator by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+4nMAssay Description:Inhibition of human plasmin by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 6.82E+4nMAssay Description:Inhibition of human recombinant tissue plasminogen activator by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human plasmin by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human recombinant factor 7a/soluble tissue factor by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of human thrombin by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.740nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.930nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human factor 10a using S2222 chromogenic substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human factor 10a using S2222 chromogenic substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human factor 10a using S2222 chromogenic substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human factor 10a using S2222 chromogenic substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human factor 10a using S2222 chromogenic substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair