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Found 83 with Last Name = 'lessen' and Initial = 'ta'
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078280((R)-2-Cyano-N-[(R)-2-(2,5-difluoro-phenoxy)-1-meth...)
Affinity DataKi:  0.0200nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078281(2-Cyano-N-[(R)-2-(2,5-difluoro-phenoxy)-1-methyl-e...)
Affinity DataKi:  0.0420nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078284(CHEMBL38912 | N-[(R)-1-(4-Bromo-phenyl)-ethyl]-5-f...)
Affinity DataKi:  0.0470nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078290((R)-2-Cyano-N-[(R)-2-(2-fluoro-phenoxy)-1-methyl-e...)
Affinity DataKi:  0.0800nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078268((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  0.0850nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078289((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  0.110nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078272((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  0.170nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078271((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  0.220nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078269((R)-2-Cyano-N-[(R)-2-(3-fluoro-phenoxy)-1-methyl-e...)
Affinity DataKi:  0.240nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078282(2-Cyano-N-[2-(2-fluoro-phenoxy)-1-methyl-ethyl]-3,...)
Affinity DataKi:  0.240nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078275((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  0.370nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078274((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  0.380nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078283(5-Fluoro-2-hydroxy-N-((R)-1-methyl-2-phenoxy-ethyl...)
Affinity DataKi:  0.440nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078277((R)-2-Cyano-N-[2-(3-fluoro-phenoxy)-1-methyl-ethyl...)
Affinity DataKi:  0.460nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078294((R)-2-Cyano-3,3-dimethyl-N-((R)-1-methyl-2-phenoxy...)
Affinity DataKi:  0.580nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078294((R)-2-Cyano-3,3-dimethyl-N-((R)-1-methyl-2-phenoxy...)
Affinity DataKi:  0.580nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078286((S)-2-Cyano-N-[(R)-2-(2,5-difluoro-phenoxy)-1-meth...)
Affinity DataKi:  0.730nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078279((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  0.830nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078293((R)-2-Cyano-N-[(R)-2-(2,3-difluoro-phenoxy)-1-meth...)
Affinity DataKi:  0.950nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078288(2-Cyano-N-[(R)-2-(4-fluoro-phenoxy)-1-methyl-ethyl...)
Affinity DataKi:  1.70nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078270((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  1.90nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078291((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  2.20nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078292(2-Cyano-3,3-dimethyl-N-(1-methyl-2-phenoxy-ethyl)-...)
Affinity DataKi:  2.80nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078295(2-Cyano-3,3-dimethyl-N-(1-methyl-3-phenyl-propyl)-...)
Affinity DataKi:  7.20nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078273((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  7.5nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078287((R)-2-Cyano-N-[(S)-2-(2,5-difluoro-phenoxy)-1-meth...)
Affinity DataKi:  7.70nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078285(2-Cyano-3,3-dimethyl-N-(3-phenyl-propyl)-butyramid...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078296((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  33nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078276((S)-2-Cyano-3,3-dimethyl-N-((R)-1-methyl-2-phenoxy...)
Affinity DataKi:  66nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078278((S)-2-Cyano-N-[(S)-2-(2,5-difluoro-phenoxy)-1-meth...)
Affinity DataKi:  97nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176285(CHEMBL440391 | ethyl 6,6-dimethyl-2-(3-(pyridin-2-...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176296(CHEMBL426298 | ethyl 6,6-dimethyl-2-(3-(pyrimidin-...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176297(CHEMBL199403 | ethyl 6,6-dimethyl-2-(3-(1-methyl-1...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176295(CHEMBL371648 | ethyl 6,6-dimethyl-2-(3-(5-methylpy...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176286(CHEMBL197815 | ethyl 6,6-dimethyl-2-(3-(2-(trifluo...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176301(CHEMBL373180 | ethyl 2-(3-(4-fluorophenylsulfonyl)...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176282(CHEMBL199961 | ethyl 6,6-dimethyl-2-(3-(1-methyl-1...)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176283(CHEMBL381660 | ethyl 6,6-dimethyl-2-(3-tosylureido...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176293(CHEMBL437897 | ethyl 2-(3-(4-cyanophenylsulfonyl)u...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176280(CHEMBL199646 | ethyl 6,6-dimethyl-2-(3-(phenylsulf...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176303(CHEMBL372400 | ethyl 2-(3-(3,4-dihydroisoquinolin-...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176282(CHEMBL199961 | ethyl 6,6-dimethyl-2-(3-(1-methyl-1...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176285(CHEMBL440391 | ethyl 6,6-dimethyl-2-(3-(pyridin-2-...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176291(CHEMBL198083 | ethyl 6,6-dimethyl-2-(3-(2-(trifluo...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176289(CHEMBL199323 | ethyl 6,6-dimethyl-2-(3-(piperidin-...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176308(CHEMBL383596 | ethyl 6-methyl-2-(3-tosylureido)-4,...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176286(CHEMBL197815 | ethyl 6,6-dimethyl-2-(3-(2-(trifluo...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176294(CHEMBL373241 | ethyl 2-(3-(indolin-1-ylsulfonyl)ur...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176295(CHEMBL371648 | ethyl 6,6-dimethyl-2-(3-(5-methylpy...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Viropharma

Curated by ChEMBL
LigandPNGBDBM50176277(CHEMBL200046 | ethyl 6,6-dimethyl-2-(3-(pyrrolidin...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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