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Found 44 with Last Name = 'rothweiler' and Initial = 'u'
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50368984(CHEMBL4164814)
Affinity DataKi:  104nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50391956(CHEMBL2152265)
Affinity DataKi:  158nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50341228(1-(4-fluoro-2-(trifluoromethyl)phenyl)-9-(1H-pyraz...)
Affinity DataKi:  252nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50368980(CHEMBL4171089)
Affinity DataKi:  383nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50368981(CHEMBL4168671)
Affinity DataKi:  575nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50368986(CHEMBL4171209)
Affinity DataKi:  1.68E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM209414(US9266890, I-24)
Affinity DataKi:  2.02E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50368985(CHEMBL4167484)
Affinity DataKi: >2.80E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataIC50:  100nMAssay Description:Binding affinity to CDK2More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50368984(CHEMBL4164814)
Affinity DataIC50:  216nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50391956(CHEMBL2152265)
Affinity DataIC50:  329nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548154(CHEMBL1532203)
Affinity DataIC50:  400nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50341228(1-(4-fluoro-2-(trifluoromethyl)phenyl)-9-(1H-pyraz...)
Affinity DataIC50:  532nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548162(CHEMBL1213041)
Affinity DataIC50:  700nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50368980(CHEMBL4171089)
Affinity DataIC50:  800nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548151(CHEMBL4747967)
Affinity DataIC50:  800nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548158(CHEMBL4794978)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548159(CHEMBL4780479)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50368981(CHEMBL4168671)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548161(CHEMBL4759909)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548157(CHEMBL1538954)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM350118(N-(6- chlorobenzo[d]thiazol-2- yl)acetamide | US10...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548164(CHEMBL4746739)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50368986(CHEMBL4171209)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548156(CHEMBL4754469)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM209414(US9266890, I-24)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50368985(CHEMBL4167484)
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548165(CHEMBL4784222)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548155(CHEMBL4759082)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548153(CHEMBL1486796)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548163(CHEMBL4741377)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50384066(CHEMBL2029515)
Affinity DataIC50:  2.36E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548160(CHEMBL4750244)
Affinity DataIC50:  2.65E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548150(CHEMBL4743605)
Affinity DataIC50:  2.81E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548166(CHEMBL4763711)
Affinity DataIC50:  2.93E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548152(CHEMBL4798633)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50548167(CHEMBL2206133)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of p60 c-SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataKd:  1.00E+5nMAssay Description:Binding affinity to CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50272597((trans-2-(4-chlorobenzyl)-3-(4-chlorophenyl)-1-oxo...)
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to human wild type Mdm2 by NMR ligand-protein binary titrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50229787((4S,5R)-Nutlin-3 | (rac)-(4,5-bis(4-chlorophenyl)-...)
Affinity DataKd:  700nMAssay Description:Binding affinity to human wild type Mdm2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50272597((trans-2-(4-chlorobenzyl)-3-(4-chlorophenyl)-1-oxo...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to human wild type Mdm2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50272597((trans-2-(4-chlorobenzyl)-3-(4-chlorophenyl)-1-oxo...)
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to human wild type Mdm2 by NMR ligand-protein binary titrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed