TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Palacky University
Palacky University
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant CDK2/cyclin EMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Palacky University
Palacky University
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Palacky£? University And Institute Of Experimental Botany Ascr
Curated by ChEMBL
Palacky£? University And Institute Of Experimental Botany Ascr
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant CDK7/cyclin H/MAT1More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMpH: 7.4 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Palacky£? University And Institute Of Experimental Botany Ascr
Curated by ChEMBL
Palacky£? University And Institute Of Experimental Botany Ascr
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant CDK5/p35More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant CDK2/cyclin EMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Institute of Experimental Botany Ascr and Palacky University
Institute of Experimental Botany Ascr and Palacky University
Affinity DataIC50: 280nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Institute of Experimental Botany Ascr and Palacky University
Institute of Experimental Botany Ascr and Palacky University
Affinity DataIC50: 350nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Institute of Experimental Botany Ascr and Palacky University
Institute of Experimental Botany Ascr and Palacky University
Affinity DataIC50: 454nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Palacky£? University And Institute Of Experimental Botany Ascr
Curated by ChEMBL
Palacky£? University And Institute Of Experimental Botany Ascr
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of human recombinant CDK7/cyclin H/MAT1More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Institute of Experimental Botany Ascr and Palacky University
Institute of Experimental Botany Ascr and Palacky University
Affinity DataIC50: 549nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
Affinity DataIC50: 800nMpH: 7.4 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMpH: 7.4 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Palacky£? University And Institute Of Experimental Botany Ascr
Curated by ChEMBL
Palacky£? University And Institute Of Experimental Botany Ascr
Curated by ChEMBL
Affinity DataIC50: 940nMAssay Description:Inhibition of human recombinant CDK5/p35More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant CDK9/cyclin T1More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Palacky University
Palacky University
Affinity DataIC50: 1.10E+3nMpH: 7.4 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMpH: 7.4 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 1.33E+3nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human recombinant CDK9/cyclin T1More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Palacky University
Palacky University
Affinity DataIC50: 2.40E+3nMpH: 7.4 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMpH: 7.4 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Palacky University
Palacky University
Affinity DataIC50: 2.50E+3nMpH: 7.4 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair