TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Competitive inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by Lineweaver-Burk plo...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Competitive inhibition of human ASK1 by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 251nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 251nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human FGFR1 (456 to 765 residues) expressed in baculovirus infected insect Sf21 cells after 25 mins u...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant ASK1 catalytic subunit (unknown origin) using MBP substrate and gamma-labeled 32P ATP incubated for 20 mins by liquid scint...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human FGFR1 (456 to 765 residues) expressed in baculovirus infected insect Sf21 cells after 25 mins u...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human FGFR1 (456 to 765 residues) expressed in baculovirus infected insect Sf21 cells after 25 mins u...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...More data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Inhibition of PARP-1 (unknown origin) after 60 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of recombinant ASK1 catalytic subunit (unknown origin) using MBP substrate and gamma-labeled 32P ATP incubated for 20 mins by liquid scint...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human FGFR1 (456 to 765 residues) expressed in baculovirus infected insect Sf21 cells after 25 mins u...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMpH: 7.5 T: 2°CAssay Description:Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of recombinant ASK1 catalytic subunit (unknown origin) using MBP substrate and gamma-labeled 32P ATP incubated for 20 mins by liquid scint...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Institute Of Molecular Biology And Genetics Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine
Curated by ChEMBL
Nas Of Ukraine
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair