Compile Data Set for Download or QSAR
maximum 50k data
Found 86 with Last Name = 'zhou' and Initial = 'xl'
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594944(CHEMBL5181703)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to GST-tagged EED (unknown origin) assessed as inhibition constant incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM223986((3R,4S)-1-[(1S)-7-fluoroindan-1-yl]-N,N-dimethyl-4...)
Affinity DataKi:  11nMAssay Description:Binding affinity to GST-tagged EED (unknown origin) assessed as inhibition constant incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594938(CHEMBL5201204)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of His-tagged EED (unknown origin) incubated for 30 mins in presence of biotinylated H3K27me3 peptide (19 to 33 aa) by alpha screening com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594938(CHEMBL5201204)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM291687(N-((5-Fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594945(CHEMBL5180485)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human N-terminal His-6 tagged EED expressed in Escherichia coli strain BL2(DE3) by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50562610(CHEMBL4779022)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of human N-terminal His-6 tagged EED expressed in Escherichia coli strain BL2(DE3) by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594944(CHEMBL5181703)
Affinity DataIC50:  18nMAssay Description:Inhibition of PRC2 complex of EZH2-EED-SUZ12 (unknown origin) using human nucleosome as substrate incubated for 70 mins in presence of [3H]SAMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594931(CHEMBL5169768)
Affinity DataIC50: <20nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594928(CHEMBL5171195)
Affinity DataIC50: <20nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594929(CHEMBL5173010)
Affinity DataIC50: <20nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50:  20nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594930(CHEMBL5188142)
Affinity DataIC50: <20nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50611346(CHEMBL5266070)
Affinity DataIC50:  22nMAssay Description:Binding affinity to BRD4 bromodomain 1 in human Ramos cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50:  45nMAssay Description:Inhibition of full length N-terminal His-6x tagged EED (1 to 441 residues) (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM291687(N-((5-Fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of EED (unknown origin) by alpha screen binding assayMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594937(CHEMBL5180270)
Affinity DataIC50: <100nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594936(CHEMBL5206890)
Affinity DataIC50: <100nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594935(CHEMBL5205261)
Affinity DataIC50: <100nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594933(CHEMBL5193972)
Affinity DataIC50: <100nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594932(CHEMBL5203240)
Affinity DataIC50: <100nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594934(CHEMBL5171965)
Affinity DataIC50: <100nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))TBA
LigandPNGBDBM50613876(CHEMBL5277869)
Affinity DataIC50:  190nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with compounds for 20 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50611350(CHEMBL5272010)
Affinity DataIC50:  240nMAssay Description:Induction of BRD4 degradation in human 231MFP cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50562612(CHEMBL4749741)
Affinity DataIC50:  247nMAssay Description:Inhibition of full length N-terminal His-6x tagged EED (1 to 441 residues) (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM223986((3R,4S)-1-[(1S)-7-fluoroindan-1-yl]-N,N-dimethyl-4...)
Affinity DataIC50:  290nMAssay Description:Inhibition of GST-tagged EED in human G-401 cells assessed as inhibition of histone trimethylation by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50562612(CHEMBL4749741)
Affinity DataIC50:  300nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase RNF114(Homo sapiens)TBA
LigandPNGBDBM50611351(CHEMBL5274261)
Affinity DataIC50:  470nMAssay Description:Inhibition of RNF114 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50236003(CHEMBL4096234)
Affinity DataIC50:  620nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 aa) binding to EED (1 to 441 residues) (unknown origin) expressed in Escherichia coli BL21-Codo...More data for this Ligand-Target Pair
TargetFolliculin-interacting protein 1(Homo sapiens)TBA
LigandPNGBDBM50611352(CHEMBL5289726)
Affinity DataIC50:  670nMAssay Description:Inhibition of FNIP1 in human HEK293T cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50235994(CHEMBL4063655)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))TBA
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with compounds for 20 mins followed by substrate addition an...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))TBA
LigandPNGBDBM50577992(CHEMBL4860003)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as a substrate incubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))TBA
LigandPNGBDBM50613874(CHEMBL5288014)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with compounds for 20 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594939(CHEMBL5187105)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human EED (76 to 441 residues) expressed in Escherichia coli strain BL21(DE3) by alpha screen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594941(CHEMBL5191512)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human EED (76 to 441 residues) expressed in Escherichia coli strain BL21(DE3) by alpha screen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50236003(CHEMBL4096234)
Affinity DataIC50:  3.28E+3nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction of global H3K27Me3 level by ELISAMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))TBA
LigandPNGBDBM50613873(CHEMBL5279203)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with compounds for 20 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))TBA
LigandPNGBDBM50577989(CHEMBL4863043)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as a substrate incubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50236003(CHEMBL4096234)
Affinity DataIC50:  4.03E+3nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))TBA
LigandPNGBDBM50577988(CHEMBL4858516)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as a substrate incubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594940(CHEMBL5174215)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human EED (76 to 441 residues) expressed in Escherichia coli strain BL21(DE3) by alpha screen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50611347(CHEMBL5277462)
Affinity DataIC50:  7.60E+3nMAssay Description:Binding affinity to BRD4 bromodomain 1 in human Ramos cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50509087(Ma''edamine A | Ma'edamine A)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))TBA
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as a substrate incubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))TBA
LigandPNGBDBM50613875(CHEMBL5270630)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with compounds for 20 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50509086(CHEMBL4539558)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50509084(CHEMBL4531006)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))TBA
LigandPNGBDBM50613877(CHEMBL5274900)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with compounds for 20 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails PubMed
Displayed 1 to 50 (of 86 total ) | Next | Last >>
Jump to: