Affinity DataIC50: 260nMAssay Description:Inhibition of wild type recombinant human thrombin expressed in BHK cells using S2238 as substrate after overnight incubation at 25 degCMore data for this Ligand-Target Pair
Affinity DataIC50: 263nMAssay Description:Inhibition of wild type recombinant human thrombin expressed in BHK cells using S2238 as substrate after overnight incubation at 25 degCMore data for this Ligand-Target Pair
Affinity DataIC50: 363nMAssay Description:Inhibition of recombinant human thrombin R97A mutant expressed in BHK cells using S2238 as substrate after overnight incubation at 25 degCMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant human thrombin R97A mutant expressed in BHK cells using S2238 as substrate after overnight incubation at 25 degCMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of recombinant wild type thrombin expressed in BHK cells assessed as spectrozyme TH hydrolysis after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 1.85E+4nMAssay Description:Antagonist activity at human TRPM8 channel expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by Fluo-4-AM dye based flu...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 4.59E+4nMAssay Description:Antagonist activity at human TRPV4 channel expressed in HEK293 cells assessed as inhibition of GSK1016790A-induced calcium flux by Fluo-4-AM dye base...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 6.16E+4nMAssay Description:Antagonist activity at human TRPM8 channel expressed in HEK293 cells assessed as inhibition of icilin-induced calcium flux by Fluo-4-AM dye based flu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 8.16E+4nMAssay Description:Antagonist activity at human TRPV1 channel expressed in human BEAS2B cells assessed as inhibition of capsaicin-induced calcium flux by Fluo-4-AM dye ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90E+4nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.21E+5nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+5nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human plasma F10a assessed as spectrozyme TH hydrolysis after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.65E+5nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.74E+5nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.75E+5nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+5nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.64E+5nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+6nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+6nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+6nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+6nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >7.00E+6nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >7.10E+6nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+7nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.60E+7nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.06E+7nMAssay Description:Inhibition of human alpha-thrombin assessed as spectrozyme TH hydrolysis after 10 mins by spectrophotometric analysisChecked by AuthorMore data for this Ligand-Target Pair