TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.700nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.700nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.800nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.800nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.800nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.900nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.970nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1nMAssay Description:Displacement of [125I]-iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by scintillation countin...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.20nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.20nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.20nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetHrh3 protein(RAT)
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.30nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.30nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]citalopram from rat brain SERTMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.30nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.30nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.30nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]-iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by scintillation countin...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.5nMAssay Description:Displacement of [125I]-iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by scintillation countin...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.5nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.5nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.60nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.60nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.60nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.60nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.70nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.70nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.70nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.80nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 1.80nMAssay Description:Displacement of [125I]-iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by scintillation countin...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]citalopram from rat brain SERTMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 2nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 2nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 2nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 2nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 2nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 2nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Johnson & Johnson Pharmaceutical Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 2.20nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair