Compile Data Set for Download or QSAR
maximum 50k data
Found 215 with Last Name = 'andes' and Initial = 'j'
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50610174(CHEMBL4293814)
Affinity DataKi:  0.340nMAssay Description:Binding affinity to human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50091405(1N-[4-cyclopropylmethyl-10-methoxy-14-oxo-(13R)-12...)
Affinity DataKi:  0.460nMAssay Description:Displacement of radioligand [3H]- DAMGO on Opioid receptor mu 1 in monkey brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50091405(1N-[4-cyclopropylmethyl-10-methoxy-14-oxo-(13R)-12...)
Affinity DataKi:  0.460nMAssay Description:Displacement of radioligand [3H]- U-69,593 on Opioid receptor kappa 1 in monkey brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50091404(1N-[4-cyclopropylmethyl-14-oxo-(13R)-12-oxa-4-azap...)
Affinity DataKi:  0.540nMAssay Description:Displacement of radioligand [3H]- DAMGO on Opioid receptor mu 1 in monkey brain membranes range; Value ranges from (0.32-0.91)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50610173(CHEMBL5280702)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50610180(CHEMBL5276588)
Affinity DataKi:  0.860nMAssay Description:Binding affinity to human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50610178(CHEMBL5289468)
Affinity DataKi:  0.920nMAssay Description:Binding affinity to human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50610177(CHEMBL5268329)
Affinity DataKi:  0.920nMAssay Description:Inhibition of human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50121205(CHEBI:18295 | Histamine)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-Histamine from human histamine 4 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50610182(CHEMBL5287235)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50066535((2E)-3-(4-chlorophenyl)-N-[(1R,13R,17S)-4-(cyclopr...)
Affinity DataKi:  1.60nMAssay Description:Displacement of radioligand [3H]- DPDPE on Opioid receptor delta 1 in monkey brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50066535((2E)-3-(4-chlorophenyl)-N-[(1R,13R,17S)-4-(cyclopr...)
Affinity DataKi:  1.60nMAssay Description:Displacement of radioligand [3H]- DAMGO on Opioid receptor mu 1 in monkey brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50066535((2E)-3-(4-chlorophenyl)-N-[(1R,13R,17S)-4-(cyclopr...)
Affinity DataKi:  1.60nMAssay Description:Displacement of radioligand [3H]- U-69,593 on Opioid receptor kappa 1 in monkey brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50121205(CHEBI:18295 | Histamine)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-Histamine from human histamine 3 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50610169(CHEMBL5270151)
Affinity DataKi:  3.10nMAssay Description:Binding affinity to human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50552436(CHEMBL4749654)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-Histamine from human histamine 3 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50091405(1N-[4-cyclopropylmethyl-10-methoxy-14-oxo-(13R)-12...)
Affinity DataKi:  4.5nMAssay Description:Displacement of radioligand [3H]- DPDPE on Opioid receptor delta 1 in monkey brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50552434(CHEMBL4747180)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]-Histamine from human histamine 3 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50610176(CHEMBL5265920)
Affinity DataKi: >10nMAssay Description:Binding affinity to human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50610170(CHEMBL5278711)
Affinity DataKi: >10nMAssay Description:Binding affinity to human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50610181(CHEMBL5270288)
Affinity DataKi: >10nMAssay Description:Binding affinity to human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50610179(CHEMBL5282002)
Affinity DataKi: >10nMAssay Description:Binding affinity to human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50610175(CHEMBL5283987)
Affinity DataKi: >10nMAssay Description:Binding affinity to human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50091404(1N-[4-cyclopropylmethyl-14-oxo-(13R)-12-oxa-4-azap...)
Affinity DataKi:  12nMAssay Description:Displacement of radioligand [3H]- U-69,593 on Opioid receptor kappa 1 in monkey brain membranes range; Value ranges from (9.7-14.2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50405713(CHEMBL4173854)
Affinity DataKi:  16nMAssay Description:Inhibition of human H3 receptor assessed as inhibition constant incubated for 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50552435(CHEMBL4756432)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-Histamine from human histamine 3 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50091404(1N-[4-cyclopropylmethyl-14-oxo-(13R)-12-oxa-4-azap...)
Affinity DataKi:  37nMAssay Description:Displacement of radioligand [3H]- DPDPE on Opioid receptor delta 1 in monkey brain membranes range; Value ranges from (34.0-43.2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50552430(CHEMBL4798369)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-Histamine from human histamine 3 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  54nMAssay Description:Binding affinity to human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50552439(CHEMBL4568949)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]-Histamine from human histamine 4 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50336482(CHEMBL1668599 | citibrasine)
Affinity DataKi:  200nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plotsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM23417(α-CA inhibitor, 4 | (-)-Epicatechin | (2R,3R)...)
Affinity DataKi:  200nMAssay Description:Noncompetitive inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50610170(CHEMBL5278711)
Affinity DataKi:  270nMAssay Description:Binding affinity to human H3 receptor assessed as inhibition constant incubated for 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50552441(CHEMBL4747747)
Affinity DataKi:  398nMAssay Description:Displacement of [3H]-Histamine from human histamine 3 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50336477(1,3,5-trihydroxy-4-methoxy-10-methyl-2,8-bis(3-met...)
Affinity DataKi:  500nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plotsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM23416(α-CA inhibitor, 3 | (+)-Catechin | (2R,3S)-2-...)
Affinity DataKi:  600nMAssay Description:Noncompetitive inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50552429(CHEMBL4752345)
Affinity DataKi:  631nMAssay Description:Displacement of [3H]-Histamine from human histamine 3 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50552444(CHEMBL4764535)
Affinity DataKi:  794nMAssay Description:Displacement of [3H]-Histamine from human histamine 3 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50552443(CHEMBL4758983)
Affinity DataKi:  794nMAssay Description:Displacement of [3H]-Histamine from human histamine 3 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50552442(CHEMBL4792753)
Affinity DataKi:  794nMAssay Description:Displacement of [3H]-Histamine from human histamine 3 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50552442(CHEMBL4792753)
Affinity DataKi:  794nMAssay Description:Displacement of [3H]-Histamine from human histamine 4 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50446567(CHEMBL3109443)
Affinity DataKi:  900nMAssay Description:Noncompetitive inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50610176(CHEMBL5265920)
Affinity DataKi:  910nMAssay Description:Binding affinity to human H3 receptor assessed as inhibition constant incubated for 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50336481(CHEMBL451705 | citrusinine I | citrusinine-I)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plotsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50336478(1,3,5-trihydroxy-4-methoxy-2-(3-methylbut-2-enyl)-...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plotsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50610169(CHEMBL5270151)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity to human H3 receptor assessed as inhibition constant incubated for 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50336476(1,3,5-trihydroxy-2,8-bis(3-methylbut-2-enyl)-10-me...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plotsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataKi:  1.20E+3nMAssay Description:Noncompetitive inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50336486(3,4-dihydro-3,5,8-trihydroxy-6-methoxy-2,2,7-trime...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plotsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Universidade Federal De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50610182(CHEMBL5287235)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity to human H3 receptor assessed as inhibition constant incubated for 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
Displayed 1 to 50 (of 215 total ) | Next | Last >>
Jump to: