TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 135nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 138nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 275nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 279nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 292nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 294nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 416nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 441nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair