Affinity DataKi: 7.00E+3nMAssay Description:Binding affinity to bovine thrombin after 3 minsMore data for this Ligand-Target Pair
Affinity DataKi: 8.60E+3nMAssay Description:Binding affinity to bovine thrombin after 3 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+4nMAssay Description:Binding affinity to bovine thrombin after 3 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+4nMAssay Description:Binding affinity to bovine thrombin after 3 minsMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of rat HMG-CoA reductase using 0.37 MBq DL-[3-14C]HMG-CoAMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of rat HMG-CoA reductase using 0.37 MBq DL-[3-14C]HMG-CoAMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 108nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of rat HMG-CoA reductase using 0.37 MBq DL-[3-14C]HMG-CoAMore data for this Ligand-Target Pair
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of tryptase (unknown origin) using t-Boc-Phe-Ser-Arg-MCA as substrate after 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 201nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Promotion of flag-tagged cIAP1 degradation in human HT1080 cells assessed as decrease in cIAPI production after 3 hrsMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Promotion of flag-tagged cIAP1 degradation in human HT1080 cells assessed as decrease in cIAPI production after 3 hrsMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Degradation promoting activity of FLAG tagged cIAP1(unknown origin) expressed in human HT1080 cells after 3 hrs by western blotting analysisMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:Inhibition of rat HMG-CoA reductase using 0.37 MBq DL-[3-14C]HMG-CoAMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Promotion of flag-tagged cIAP1 degradation in human HT1080 cells assessed as decrease in cIAPI production after 3 hrsMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 850nMAssay Description:Inhibition of rat HMG-CoA reductase using 0.37 MBq DL-[3-14C]HMG-CoAMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.06E+3nMAssay Description:Promotion of flag-tagged cIAP1 degradation in human HT1080 cells assessed as decrease in cIAPI production after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-Arg-pNA.HCl as substrate after 5 mins by colorimetric analysisMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of rat HMG-CoA reductase using 0.37 MBq DL-[3-14C]HMG-CoAMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Promotion of flag-tagged cIAP1 degradation in human HT1080 cells assessed as decrease in cIAPI production after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.54E+3nMAssay Description:Promotion of flag-tagged cIAP1 degradation in human HT1080 cells assessed as decrease in cIAPI production after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of rat HMG-CoA reductase using 0.37 MBq DL-[3-14C]HMG-CoAMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.86E+3nMAssay Description:Degradation promoting activity of FLAG tagged cIAP1(unknown origin) expressed in human HT1080 cells after 3 hrs by western blotting analysisMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.89E+3nMAssay Description:Degradation promoting activity of FLAG tagged cIAP1(unknown origin) expressed in human HT1080 cells after 3 hrs by western blotting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of rat HMG-CoA reductase using 0.37 MBq DL-[3-14C]HMG-CoAMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 4.47E+3nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 4.69E+3nMAssay Description:Promotion of flag-tagged cIAP1 degradation in human HT1080 cells assessed as decrease in cIAPI production after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of thrombin (unknown origin) using t-Boc-Val-Pro-Arg-MCA as substrate after 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of rat HMG-CoA reductase using 0.37 MBq DL-[3-14C]HMG-CoAMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Transactivational antagonist activity at human LXRbeta transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced lucif...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 9.20E+3nMAssay Description:Promotion of flag-tagged cIAP1 degradation in human HT1080 cells assessed as decrease in cIAPI production after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+3nMAssay Description:Transactivational antagonist activity at human LXRbeta transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced lucif...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Transactivational antagonist activity at human LXRbeta transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced lucif...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair