Compile Data Set for Download or QSAR
maximum 50k data
Found 217 with Last Name = 'araki' and Initial = 'y'
TargetAbscisic acid 8'-hydroxylase 3(Arabidopsis thaliana)
Shizuoka University

Curated by ChEMBL
LigandPNGBDBM50184728(5-((1S,2S,6S)-1,2-dihydroxy-6-methylcyclohexyl)pen...)
Affinity DataKi:  140nMAssay Description:Inhibition of Arabidopsis recombinant CYP707A3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50384416(CHEMBL2111553 | CHEMBL291536 | SB-334867)
Affinity DataKi:  670nMAssay Description:Binding affinity to adenosine 2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50384416(CHEMBL2111553 | CHEMBL291536 | SB-334867)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to 5HT2c receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAbscisic acid 8'-hydroxylase 3(Arabidopsis thaliana)
Shizuoka University

Curated by ChEMBL
LigandPNGBDBM50174070((+)-(2Z,4E)-5-((1S,6S)-1-hydroxy-2,2,6-trimethylcy...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of Arabidopsis recombinant CYP707A3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208487(US9266870, 3)
Affinity DataIC50:  0.700nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50260997(CHEMBL4073607)
Affinity DataIC50:  0.767nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208524(US9266870, 40 | US9266870, 49)
Affinity DataIC50:  0.800nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208519(US9266870, 35)
Affinity DataIC50:  0.800nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50261002(CHEMBL4059968)
Affinity DataIC50:  0.820nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208511(US9266870, 27)
Affinity DataIC50:  0.900nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208525(US9266870, 41)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208525(US9266870, 41)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208519(US9266870, 35)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208521(US9266870, 37)
Affinity DataIC50:  1.10nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50260978(CHEMBL4091475)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50260979(CHEMBL4069535)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208487(US9266870, 3)
Affinity DataIC50:  1.20nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208513(US9266870, 29)
Affinity DataIC50:  1.20nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50260983(CHEMBL4089060)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50260963(CHEMBL4077821)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50260976(CHEMBL4081186)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208524(US9266870, 40 | US9266870, 49)
Affinity DataIC50:  1.40nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50260977(CHEMBL4070565)
Affinity DataIC50:  1.40nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50260985(CHEMBL4100428)
Affinity DataIC50:  1.60nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50260975(CHEMBL4095852)
Affinity DataIC50:  1.60nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50260985(CHEMBL4100428)
Affinity DataIC50:  1.60nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208521(US9266870, 37)
Affinity DataIC50:  1.70nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50261000(CHEMBL4080357)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50261003(CHEMBL4060971)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50261019(CHEMBL4087320)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50260987(CHEMBL4088347)
Affinity DataIC50:  1.90nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50260984(CHEMBL4060868)
Affinity DataIC50:  1.90nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Sus scrofa)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50091535(4-tert-Butyl-N-[4-(3-methoxy-phenylsulfanyl)-5-(4-...)
Affinity DataIC50:  2nMAssay Description:Binding affinity towards displacement of [125 I] ET-3 from COS-7 cells transfected with porcine Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50261005(CHEMBL4090659)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208522(US9266870, 38)
Affinity DataIC50:  2.10nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208518(US9266870, 34)
Affinity DataIC50:  2.20nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208501(US9266870, 17 | US9266870, 22)
Affinity DataIC50:  2.40nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208512(US9266870, 28)
Affinity DataIC50:  2.40nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208501(US9266870, 17 | US9266870, 22)
Affinity DataIC50:  2.40nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50261006(CHEMBL4065909)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50261002(CHEMBL4059968)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208527(US9266870, 43)
Affinity DataIC50:  2.60nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208514(US9266870, 30)
Affinity DataIC50:  2.60nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50260978(CHEMBL4091475)
Affinity DataIC50:  2.70nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208529(US9266870, 45)
Affinity DataIC50:  2.70nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50261028(CHEMBL3398466)
Affinity DataIC50:  2.80nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208511(US9266870, 27)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208514(US9266870, 30)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50261022(CHEMBL4069644)
Affinity DataIC50:  3.10nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208488(US9266870, 4)
Affinity DataIC50:  3.20nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 217 total ) | Next | Last >>
Jump to: