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Found 154 with Last Name = 'beevers' and Initial = 're'
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211428(CHEMBL245936 | N-ethyl-4-(4-(2-phenyl-1H-indol-3-y...)
Affinity DataIC50:  5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211428(CHEMBL245936 | N-ethyl-4-(4-(2-phenyl-1H-indol-3-y...)
Affinity DataIC50:  5nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidase 1(Dermatophagoides pteronyssinus (European house dus...)
St George'S Hosptial Medical School

US Patent
LigandPNGBDBM103023(US8541363, PVA-039)
Affinity DataIC50:  6.30nMAssay Description:The fluorogenic substrate used for measuring Der p 1 proteolytic activity was 2-aminobenzoylvalylalanylnorleucylseryl-(3-nitro)tyrosinyl aspartamide....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPeptidase 1(Dermatophagoides pteronyssinus (European house dus...)
St George'S Hosptial Medical School

US Patent
LigandPNGBDBM103022(US8541363, PVA-037)
Affinity DataIC50:  7.85nMAssay Description:The fluorogenic substrate used for measuring Der p 1 proteolytic activity was 2-aminobenzoylvalylalanylnorleucylseryl-(3-nitro)tyrosinyl aspartamide....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211424(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211436(2-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50:  13nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidase 1(Dermatophagoides pteronyssinus (European house dus...)
St George'S Hosptial Medical School

US Patent
LigandPNGBDBM103021(US8541363, PVA-038)
Affinity DataIC50:  13.3nMAssay Description:The fluorogenic substrate used for measuring Der p 1 proteolytic activity was 2-aminobenzoylvalylalanylnorleucylseryl-(3-nitro)tyrosinyl aspartamide....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211430((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Affinity DataIC50:  14nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211436(2-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50:  14nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidase 1(Dermatophagoides pteronyssinus (European house dus...)
St George'S Hosptial Medical School

US Patent
LigandPNGBDBM103020(US8541363, PVA-026)
Affinity DataIC50:  14nMAssay Description:The fluorogenic substrate used for measuring Der p 1 proteolytic activity was 2-aminobenzoylvalylalanylnorleucylseryl-(3-nitro)tyrosinyl aspartamide....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211438(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211430((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Affinity DataIC50:  15nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211443((3S)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylam...)
Affinity DataIC50:  15nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211426(2-((R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211429((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Affinity DataIC50:  18nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211428(CHEMBL245936 | N-ethyl-4-(4-(2-phenyl-1H-indol-3-y...)
Affinity DataIC50:  22nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211436(2-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50:  22nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211424(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211429((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Affinity DataIC50:  26nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211444(CHEMBL245535 | N-(2-(4-(5-chloro-4-(1H-indol-3-yl)...)
Affinity DataIC50:  28nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211443((3S)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylam...)
Affinity DataIC50:  29nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211426(2-((R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl...)
Affinity DataIC50:  31nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211426(2-((R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl...)
Affinity DataIC50:  31nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211443((3S)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylam...)
Affinity DataIC50:  32nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211434(CHEMBL245533 | ethyl 4-(5-chloro-4-(1H-indol-3-yl)...)
Affinity DataIC50:  37nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211438(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50:  37nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211440(4-(5-chloro-4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimi...)
Affinity DataIC50:  41nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211432(1-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50:  45nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211444(CHEMBL245535 | N-(2-(4-(5-chloro-4-(1H-indol-3-yl)...)
Affinity DataIC50:  46nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211442(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50:  47nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211430((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Affinity DataIC50:  48nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211434(CHEMBL245533 | ethyl 4-(5-chloro-4-(1H-indol-3-yl)...)
Affinity DataIC50:  49nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211440(4-(5-chloro-4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimi...)
Affinity DataIC50:  55nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211432(1-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50:  57nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211424(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50:  57nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211427(4-(4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yla...)
Affinity DataIC50:  59nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211439((3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylam...)
Affinity DataIC50:  60nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211442(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50:  62nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211446(1-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50:  67nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211431(4-(5-cyano-4-(6-fluoro-1H-indol-3-yl)pyrimidin-2-y...)
Affinity DataIC50:  67nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211423(4-(4-(1H-indol-1-yl)pyrimidin-2-ylamino)-N-ethylpi...)
Affinity DataIC50:  71nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211441(4-(4-(1H-indol-3-yl)pyrimidin-2-ylamino)-N-ethylpi...)
Affinity DataIC50:  74nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182922(1-(benzyloxy)-3-(3-(pyridin-4-yl)-1H-indol-6-yl)ur...)
Affinity DataIC50:  76nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211434(CHEMBL245533 | ethyl 4-(5-chloro-4-(1H-indol-3-yl)...)
Affinity DataIC50:  82nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50182920(1-methyl-1-phenyl-3-(3-(pyridin-4-yl)-1H-indol-6-y...)
Affinity DataIC50:  84nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211446(1-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50:  85nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211439((3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylam...)
Affinity DataIC50:  88nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211431(4-(5-cyano-4-(6-fluoro-1H-indol-3-yl)pyrimidin-2-y...)
Affinity DataIC50:  92nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211439((3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylam...)
Affinity DataIC50:  107nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211432(1-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50:  120nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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