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Found 57 with Last Name = 'bergfors' and Initial = 't'
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188493(Triazole 1e)
Affinity DataIC50:  50nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate assessed as formation of MEP measured every 5 secs for 180 secs by spectrophotome...More data for this Ligand-Target Pair
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188489(Triazole 1a)
Affinity DataIC50:  90nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188495(Biaryl 2a)
Affinity DataIC50:  120nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188495(Biaryl 2a)
Affinity DataIC50:  130nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188492(Triazole 1d)
Affinity DataIC50:  140nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437793(CHEMBL2407193)
Affinity DataIC50:  140nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188491(Triazole 1c)
Affinity DataIC50:  150nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50380000(CHEMBL258981)
Affinity DataIC50:  159nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50081647(CHEMBL3422252)
Affinity DataIC50:  205nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437797(CHEMBL2407184)
Affinity DataIC50:  320nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)
Affinity DataIC50:  438nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188496(Biaryl 2b)
Affinity DataIC50:  550nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188493(Triazole 1e)
Affinity DataIC50:  690nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437803(CHEMBL2407185)
Affinity DataIC50:  830nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50081649(CHEMBL3422255)
Affinity DataIC50:  843nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188494(Triazole 1f)
Affinity DataIC50:  1.09E+3nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188490(Triazole 1b)
Affinity DataIC50:  1.13E+3nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50380000(CHEMBL258981)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437792(CHEMBL2407194)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437806(CHEMBL2407346)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437804(CHEMBL2407348)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50422666(CHEMBL607492)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188492(Triazole 1d)
Affinity DataIC50:  2.82E+3nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437805(CHEMBL2407347)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188489(Triazole 1a)
Affinity DataIC50:  5.50E+3nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50081650(CHEMBL3422256)
Affinity DataIC50:  6.67E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437801(CHEMBL2407188)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081647(CHEMBL3422252)
Affinity DataIC50:  7.13E+3nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437796(CHEMBL2407187)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437802(CHEMBL2407186)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081649(CHEMBL3422255)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188491(Triazole 1c)
Affinity DataIC50:  1.04E+4nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188490(Triazole 1b)
Affinity DataIC50: >1.25E+4nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437794(CHEMBL2407192)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
TargetPantothenate kinase(Mycobacterium tuberculosis ATCC 25618/H37Rv)
Uppsala University

LigandPNGBDBM188494(Triazole 1f)
Affinity DataIC50:  1.40E+4nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437795(CHEMBL2407189)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437800(CHEMBL2407190)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437808(CHEMBL2407195)
Affinity DataIC50:  2.72E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50081648(CHEMBL3422254)
Affinity DataIC50:  3.14E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437807(CHEMBL2407196)
Affinity DataIC50:  4.87E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437798(CHEMBL2407349)
Affinity DataIC50:  6.77E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437799(CHEMBL2407191)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50422660(CHEMBL607357)
Affinity DataIC50:  1.56E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50422642(CHEMBL607355)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50422649(CHEMBL607353)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081650(CHEMBL3422256)
Affinity DataIC50:  2.73E+5nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437797(CHEMBL2407184)
Affinity DataKd:  210nMAssay Description:Binding affinity to Mycobacterium tuberculosis DXR assessed as dissociation constant by spectrofluorimetric analysis in presence of NADPH and MnCl2More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50437798(CHEMBL2407349)
Affinity DataKd:  320nMAssay Description:Binding affinity to Mycobacterium tuberculosis DXR assessed as dissociation constant by spectrofluorimetric analysis in presence of NADPH and MnCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50181148(1-(3,4-dichlorophenyl)-3-(N-hydroxyacetamido)propy...)
Affinity DataKd:  360nMAssay Description:Binding affinity to Mycobacterium tuberculosis DXR assessed as dissociation constant by spectrofluorimetric analysis in presence of NADPH and MnCl2More data for this Ligand-Target Pair
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