TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 170nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 380nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 480nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 510nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 530nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 580nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 620nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 720nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 740nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 770nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 820nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 840nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 850nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 930nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 930nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 2.20E+3nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 3.30E+3nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 5.30E+3nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Agonist activity at human FSHR receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter ge...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Antagonist activity at human GnRHR expressed in CHO cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 309nMAssay Description:Antagonist activity at human GnRHR expressed in CHO cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 324nMAssay Description:Agonist activity at human FSHR receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter ge...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 355nMAssay Description:Antagonist activity at human GnRHR expressed in CHO cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Antagonist activity at human recombinant GnRHR expressed in CHOK1 cells assessed as reduction in luminescence signal by luciferase reporter gene assa...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Antagonist activity at human recombinant GnRHR expressed in CHOK1 cells assessed as reduction in luminescence signal by luciferase reporter gene assa...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Antagonist activity at human recombinant GnRHR expressed in CHOK1 cells assessed as reduction in luminescence signal by luciferase reporter gene assa...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Antagonist activity at human recombinant GnRHR expressed in CHOK1 cells assessed as reduction in luminescence signal by luciferase reporter gene assa...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 468nMAssay Description:Antagonist activity at human GnRHR expressed in CHO cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 520nMAssay Description:Antagonist activity at human recombinant GnRHR expressed in CHOK1 cells assessed as reduction in luminescence signal by luciferase reporter gene assa...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 525nMAssay Description:Antagonist activity at human GnRHR expressed in CHO cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 676nMAssay Description:Antagonist activity at human GnRHR expressed in CHO cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 676nMAssay Description:Antagonist activity at human GnRHR expressed in CHO cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Antagonist activity at human recombinant GnRHR expressed in CHOK1 cells assessed as reduction in luminescence signal by luciferase reporter gene assa...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 724nMAssay Description:Antagonist activity at human GnRHR expressed in CHO cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 724nMAssay Description:Antagonist activity at human GnRHR expressed in CHO cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 832nMAssay Description:Antagonist activity at human GnRHR expressed in CHO cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 832nMAssay Description:Antagonist activity at human GnRHR expressed in CHO cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Agonist activity at human FSHR receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter ge...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 955nMAssay Description:Antagonist activity at human GnRHR expressed in CHO cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human GnRHR expressed in CHO cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair