BindingDB PrimarySearch_ki

Found 140 with Last Name = 'brackeen' and Initial = 'mf'

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50085044((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...)

Ki: 1.10nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase CHEMBL MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed MMDB
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418564(CHEMBL423026)

Ki: 1.5nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418568(CHEMBL146822)

Ki: 3.30nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50000012(CHEMBL147826)

Ki: 3.70nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50064451(5-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-be...)

Ki: 4.30nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418575(CHEMBL358137)

Ki: 5.10nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418563(CHEMBL148301)

Ki: 5.20nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418571(CHEMBL346219)

Ki: 6.5nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418557(CHEMBL1785028)

Ki: 12nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418557(CHEMBL1785028)

Ki: 12nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50029954((7R,7aS)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...)

Ki: 27nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50049244(5-{4-[2-(Benzooxazol-2-yl-methyl-amino)-ethoxy]-be...)

Ki: 27nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50000010(CHEMBL146614)

Ki: 28nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470745(CHEMBL286840)

Ki: 30nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418573(CHEMBL147694)

Ki: 32nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418566(CHEMBL146322)

Ki: 33nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470752(CHEMBL38328)

Ki: 34nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470756(CHEMBL37453)

Ki: 46nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)

Ki: 47nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

ChEBI
CHEMBL PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418562(CHEMBL357479)

Ki: 51nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470750(CHEMBL286291)

Ki: 56nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470731(CHEMBL146946)

Ki: 59nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470736(CHEMBL37029)

Ki: 60nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50029955((7R,7aR)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...)

Ki: 63nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470740(CHEMBL264851)

Ki: 65nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470754(CHEMBL288928)

Ki: 68nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50029951((7R,7aS)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-tet...)

Ki: 70nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470725(CHEMBL36318)

Ki: 71nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470743(CHEMBL422578)

Ki: 71nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418567(CHEMBL148060)

Ki: 85nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470748(CHEMBL36724 | TCMDC-131880)

Ki: 89nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470735(CHEMBL287687)

Ki: 89nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470739(CHEMBL413274)

Ki: 91nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470727(CHEMBL2093097)

Ki: 100nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50085048((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(methyl-pyri...)

Ki: 104nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase CHEMBL MCE
KEGG PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470755(CHEMBL36626)

Ki: 110nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418574(CHEMBL146123)

Ki: 123nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470749(CHEMBL34846)

Ki: 145nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470729(CHEMBL284970)

Ki: 155nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470730(CHEMBL35213)

Ki: 158nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470751(CHEMBL286391)

Ki: 158nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418572(CHEMBL359377)

Ki: 162nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL

PNG

BDBM50418569(CHEMBL145829)

Ki: 162nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470738(CHEMBL36728)

Ki: 182nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470737(CHEMBL290191)

Ki: 182nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470726(CHEMBL1169563)

Ki: 186nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470747(CHEMBL38219)

Ki: 195nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)

Ki: 221nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL MCE
PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)

Ki: 224nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL MCE
PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research

Curated by ChEMBL

PNG

BDBM50470728(CHEMBL285532)

Ki: 269nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Displayed 1 to 50 (of 140 total ) | Next | Last >>

Filter my 140 hits

Targets 7▿
- Peroxisome proliferator-activated receptor gamma 86
- cAMP-specific 3',5'-cyclic phosphodiesterase 4B 43
- Peroxisome proliferator-activated receptor alpha 5
- Peroxisome proliferator-activated receptor delta 3
- cGMP-specific 3',5'-cyclic phosphodiesterase 1
- cGMP-dependent 3',5'-cyclic phosphodiesterase 1
- High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A 1
Publications 4▿
- J Med Chem 41: 5020-36 (1999) 94
- J Med Chem 38: 1505-10 (1995) 34
- J Med Chem 38: 4848-54 (1996) 9
- J Med Chem 38: 4972-5 (1996) 3
Institutions 3▿
- Glaxo Wellcome Research And Development 94
- Glaxo Research Institute 34
- Glaxo Wellcome Research 12
Affinity: 0.34 to 1.0E+5 nM▿
- Ki 89
- EC50 51
- Affinity ≤ nM
Xtal structures: 4
Docked structures: 0
Catalog Cmpds: 7