TargetCholinesterase(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 0.131nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.850nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by ChEMBL
Clinical Research Institute Of Montreal
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by ChEMBL
Clinical Research Institute Of Montreal
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by ChEMBL
Clinical Research Institute Of Montreal
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by ChEMBL
Clinical Research Institute Of Montreal
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by ChEMBL
Clinical Research Institute Of Montreal
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by ChEMBL
Clinical Research Institute Of Montreal
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by ChEMBL
Clinical Research Institute Of Montreal
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by ChEMBL
Clinical Research Institute Of Montreal
Curated by ChEMBL
Affinity DataKi: 3.99nMAssay Description:Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding siteMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by ChEMBL
Clinical Research Institute Of Montreal
Curated by ChEMBL
Affinity DataKi: 3.99nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Ability to displace [3H]DAMGO from human recombinant Opioid receptor mu 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Ability to displace [3H]DAMGO from human recombinant Opioid receptor mu 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by ChEMBL
Clinical Research Institute Of Montreal
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by ChEMBL
Clinical Research Institute Of Montreal
Curated by ChEMBL
Affinity DataKi: 6.40nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.70nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.10nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by ChEMBL
Clinical Research Institute Of Montreal
Curated by ChEMBL
Affinity DataKi: 9.40nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by ChEMBL
Clinical Research Institute Of Montreal
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding siteMore data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition meas...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair