Compile Data Set for Download or QSAR
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Found 383 with Last Name = 'brandt' and Initial = 'w'
TargetCholinesterase(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50234795(CHEMBL4089082)
Affinity DataKi:  0.131nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)
Affinity DataKi:  0.200nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122859(22-cyclopropylmethyl-7-[2-(1-iminobutylamino)ethyl...)
Affinity DataKi:  0.25nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122869(22-cyclopropylmethyl-7-[2-(1-iminopropylamino)ethy...)
Affinity DataKi:  0.280nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122862(22-cyclopropylmethyl-7-[2-(1-iminoethylamino)ethyl...)
Affinity DataKi:  0.290nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122863(22-cyclopropylmethyl-7-[2-(1-iminopentylamino)ethy...)
Affinity DataKi:  0.300nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122855(1N-{2-[22-cyclopropylmethyl-2,16-dihydroxy-14-oxa-...)
Affinity DataKi:  0.680nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122852(1N-{2-[22-cyclopropylmethyl-2,16-dihydroxy-14-oxa-...)
Affinity DataKi:  0.850nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal

Curated by ChEMBL
LigandPNGBDBM50041142((S)-2-Amino-N-((5S,8S,16aR)-5-benzyl-4,7,13,16-tet...)
Affinity DataKi:  0.880nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122865(22-cyclopropylmethyl-7-[2-(1-imino-3-methylbutylam...)
Affinity DataKi:  1.40nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122856(22-cyclopropylmethyl-7-(2-imino-2-pentylaminoethyl...)
Affinity DataKi:  1.40nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122860(1N-{2-[22-cyclopropylmethyl-2,16-dihydroxy-14-oxa-...)
Affinity DataKi:  1.60nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122864(22-cyclopropylmethyl-7-(2-imino-2-propylaminoethyl...)
Affinity DataKi:  1.60nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal

Curated by ChEMBL
LigandPNGBDBM50041146((S)-2-Amino-3-(4-hydroxy-phenyl)-N-[(5S,8R,16aR)-5...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122851(7N-(4-methoxybenzyl)-22-cyclopropylmethyl-2,16-dih...)
Affinity DataKi:  2.10nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122853(7N-phenethyl-22-cyclopropylmethyl-2,16-dihydroxy-1...)
Affinity DataKi:  2.20nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122857(22-cyclopropylmethyl-7-(6-hexylaminocarbonylaminoe...)
Affinity DataKi:  2.30nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122861(22-cyclopropylmethyl-7-(2-ethylaminocarbonylaminoe...)
Affinity DataKi:  2.40nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299858(1-(3,4-Dimethoxyphenyl)-N-(3-(5-methyl-1H-imidazol...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122866(22-cyclopropylmethyl-7-(4-butylaminocarbonylaminoe...)
Affinity DataKi:  2.60nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal

Curated by ChEMBL
LigandPNGBDBM50041148((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8S,13aR)-5...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal

Curated by ChEMBL
LigandPNGBDBM50041144((S)-2-Amino-N-((5S,8S)-5-benzyl-4,7,13,16-tetraoxo...)
Affinity DataKi:  3nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal

Curated by ChEMBL
LigandPNGBDBM50041144((S)-2-Amino-N-((5S,8S)-5-benzyl-4,7,13,16-tetraoxo...)
Affinity DataKi:  3nMAssay Description:Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122860(1N-{2-[22-cyclopropylmethyl-2,16-dihydroxy-14-oxa-...)
Affinity DataKi:  3.10nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal

Curated by ChEMBL
LigandPNGBDBM50041141((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8R,16aR)-5...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122853(7N-phenethyl-22-cyclopropylmethyl-2,16-dihydroxy-1...)
Affinity DataKi:  3.5nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122852(1N-{2-[22-cyclopropylmethyl-2,16-dihydroxy-14-oxa-...)
Affinity DataKi:  3.70nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal

Curated by ChEMBL
LigandPNGBDBM50041145((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8S)-5-naph...)
Affinity DataKi:  3.99nMAssay Description:Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal

Curated by ChEMBL
LigandPNGBDBM50041145((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8S)-5-naph...)
Affinity DataKi:  3.99nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122851(7N-(4-methoxybenzyl)-22-cyclopropylmethyl-2,16-dih...)
Affinity DataKi:  4.60nMAssay Description:Ability to displace [3H]DAMGO from human recombinant Opioid receptor mu 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122866(22-cyclopropylmethyl-7-(4-butylaminocarbonylaminoe...)
Affinity DataKi:  4.80nMAssay Description:Ability to displace [3H]DAMGO from human recombinant Opioid receptor mu 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122864(22-cyclopropylmethyl-7-(2-imino-2-propylaminoethyl...)
Affinity DataKi:  5.30nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122858(22-cyclopropylmethyl-7-(2-heptylamino-2-iminoethyl...)
Affinity DataKi:  5.60nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)
Affinity DataKi:  5.70nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal

Curated by ChEMBL
LigandPNGBDBM50041143((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8S,16aR)-5...)
Affinity DataKi:  5.90nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122867(7N-(4-phenylbutyl)-22-cyclopropylmethyl-2,16-dihyd...)
Affinity DataKi:  6.20nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299853(1-(3,4-Dimethoxyphenyl)-3-(3-(5-methyl-1H-imidazol...)
Affinity DataKi:  6.30nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122866(22-cyclopropylmethyl-7-(4-butylaminocarbonylaminoe...)
Affinity DataKi:  6.30nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal

Curated by ChEMBL
LigandPNGBDBM50041149((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5R,8R,15aS)-5...)
Affinity DataKi:  6.40nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122858(22-cyclopropylmethyl-7-(2-heptylamino-2-iminoethyl...)
Affinity DataKi:  7.30nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122851(7N-(4-methoxybenzyl)-22-cyclopropylmethyl-2,16-dih...)
Affinity DataKi:  7.40nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122855(1N-{2-[22-cyclopropylmethyl-2,16-dihydroxy-14-oxa-...)
Affinity DataKi:  7.70nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122857(22-cyclopropylmethyl-7-(6-hexylaminocarbonylaminoe...)
Affinity DataKi:  8.10nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  9.40nMAssay Description:Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal

Curated by ChEMBL
LigandPNGBDBM50041146((S)-2-Amino-3-(4-hydroxy-phenyl)-N-[(5S,8R,16aR)-5...)
Affinity DataKi:  10nMAssay Description:Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50234798(CHEMBL4091899)
Affinity DataKi:  10nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122868(7N-benzyl-22-cyclopropylmethyl-2,16-dihydroxy-14-o...)
Affinity DataKi:  10nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122868(7N-benzyl-22-cyclopropylmethyl-2,16-dihydroxy-14-o...)
Affinity DataKi:  11nMAssay Description:Ability to displace [3H]DPDPE from human recombinant Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50122861(22-cyclopropylmethyl-7-(2-ethylaminocarbonylaminoe...)
Affinity DataKi:  12nMAssay Description:Ability to displace [3H]U-69593 from human recombinant Opioid receptor kappa 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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