Affinity DataIC50: <1nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against p56 Lck tyrosine kinase at a concentration of 5 uM ATP.More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibitory activity against p56 Lck tyrosine kinase at a concentration of 5 uM ATP.More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibitory activity against p56 Lck tyrosine kinase at a concentration of 5 uM ATP.More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibitory activity against p56 Lck tyrosine kinase at a concentration of 5 uM ATP.More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of C-terminal His-tagged Syk catalytic domain (356 to 635 residues) (unknown origin) using biotin-TYR1 as substrate after 60 mins by TR-FR...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of C-terminal His-tagged Syk catalytic domain (356 to 635 residues) (unknown origin) using biotin-TYR1 as substrate after 60 mins by TR-FR...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against p56 Lck tyrosine kinase at a concentration of 5 microM ATP.More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against p56 Lck tyrosine kinase at a concentration of 5 microM ATP.More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of C-terminal His-tagged Syk catalytic domain (356 to 635 residues) (unknown origin) using biotin-TYR1 as substrate after 60 mins by TR-FR...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of C-terminal His-tagged Syk catalytic domain (356 to 635 residues) (unknown origin) using biotin-TYR1 as substrate after 60 mins by TR-FR...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against p56 Lck tyrosine kinase at a concentration of 5 microM ATP.More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Syk (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Syk (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against p56 Lck tyrosine kinase at a concentration of 5 microM ATP.More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against p56 Lck tyrosine kinase at a concentration of 5 microM ATP.More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of C-terminal His-tagged Syk catalytic domain (356 to 635 residues) (unknown origin) using biotin-TYR1 as substrate after 60 mins by TR-FR...More data for this Ligand-Target Pair
Affinity DataIC50: 12.5nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of C-terminal His-tagged Syk catalytic domain (356 to 635 residues) (unknown origin) using biotin-TYR1 as substrate after 60 mins by TR-FR...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against anti-CD3 mAb-induced IL2 production in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against p56 Lck tyrosine kinase at a concentration of 5 microM ATP.More data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against anti-CD3 mAb-induced IL2 production in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against p56 Lck tyrosine kinase at a concentration of 5 microM ATP.More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration required against 5-lipoxygenase activity in cytosolic fractions of human neutrophilsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of C-terminal His-tagged Syk catalytic domain (356 to 635 residues) (unknown origin) using biotin-TYR1 as substrate after 60 mins by TR-FR...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of Syk (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair