Found 96 with Last Name = 'buttrick' and Initial = 'b' TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 0.460nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 0.460nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 3.10nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 4.30nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 5.10nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 5.10nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 18nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 18nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: <20nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
3D Structure (crystal)TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 60nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 110nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 120nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 140nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 140nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 220nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 240nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 270nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 340nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 470nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 480nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 520nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 660nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 680nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 680nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 930nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.01E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.22E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.25E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.56E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.58E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.63E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.69E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.76E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.90E+3nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 2.30E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 2.57E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 2.60E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 2.95E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 3.15E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
