Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.26nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 5.01nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 7.94nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 7.94nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 19.9nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 19.9nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 25.1nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 25.1nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 25.1nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 25.1nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 31.6nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 31.6nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 31.6nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 31.6nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 31.6nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 50.1nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 50.1nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 63.1nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 63.1nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 79.4nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 79.4nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 79.4nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 126nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 126nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 158nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 316nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 316nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 316nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.26E+3nMAssay Description:Displacement of [3H]dofetolide from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Compound was tested for inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing human delta opioid receptorMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataIC50: >100nMAssay Description:In vitro inhibition of human Glycine Transporter type-1.More data for this Ligand-Target Pair