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Found 337 with Last Name = 'chan' and Initial = 'cs'
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111856(CHEMBL21249 | {(R)-2-Amino-4-[benzo[1,3]dioxol-5-y...)
Affinity DataIC50:  0.0240nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111848((R)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111848((R)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565052(CHEMBL4792609)
Affinity DataIC50:  0.820nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565051(CHEMBL4783930)
Affinity DataIC50:  0.830nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565052(CHEMBL4792609)
Affinity DataIC50:  0.880nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565051(CHEMBL4783930)
Affinity DataIC50:  0.880nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565052(CHEMBL4792609)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565053(CHEMBL4790157)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565051(CHEMBL4783930)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565052(CHEMBL4792609)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50102948(CHEMBL279023 | {(R)-4-[Benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50:  3.90nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM81939(CAS_52-53-9 | NSC_62969 | VERAPAMIL)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50102948(CHEMBL279023 | {(R)-4-[Benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50:  3.90nMAssay Description:Inhibitory activity against procollagen C-Proteinase (PCP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565054(CHEMBL4783872)
Affinity DataIC50:  4nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565054(CHEMBL4783872)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111808(CHEMBL282484 | {(R)-2-Amino-4-[benzo[1,3]dioxol-5-...)
Affinity DataIC50:  4.60nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565053(CHEMBL4790157)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565051(CHEMBL4783930)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565054(CHEMBL4783872)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565053(CHEMBL4790157)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 5 uM measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565053(CHEMBL4790157)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565054(CHEMBL4783872)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111840((R)-N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-(2-tr...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565053(CHEMBL4790157)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565052(CHEMBL4792609)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 5 uM measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565052(CHEMBL4792609)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 2.5 uM measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565051(CHEMBL4783930)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of ABCB1 in human KB-VIN cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565053(CHEMBL4790157)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 2.5 uM measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM81939(CAS_52-53-9 | NSC_62969 | VERAPAMIL)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565051(CHEMBL4783930)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 5 uM measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565052(CHEMBL4792609)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of ABCB1 in human KB-VIN cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM81939(CAS_52-53-9 | NSC_62969 | VERAPAMIL)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 2.5 uM measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565052(CHEMBL4792609)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 5 uM measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM81939(CAS_52-53-9 | NSC_62969 | VERAPAMIL)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 2.5 uM measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565051(CHEMBL4783930)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 5 uM measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565051(CHEMBL4783930)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of human full-length ABCB1 expressed in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincris...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50102988(CHEMBL21486 | {(R)-4-[Benzo[1,3]dioxol-5-ylmethyl-...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against procollagen C-Proteinase (PCP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50102988(CHEMBL21486 | {(R)-4-[Benzo[1,3]dioxol-5-ylmethyl-...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565051(CHEMBL4783930)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 2.5 uM measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565052(CHEMBL4792609)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of human full-length ABCB1 expressed in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincris...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565052(CHEMBL4792609)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 2.5 uM measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111842((R)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against procollagen C-proteinase (PCP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565054(CHEMBL4783872)
Affinity DataIC50:  10nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 5 uM measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565053(CHEMBL4790157)
Affinity DataIC50:  11nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 5 uM measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565051(CHEMBL4783930)
Affinity DataIC50:  11nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 2.5 uM measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565054(CHEMBL4783872)
Affinity DataIC50:  11nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 2.5 uM measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565053(CHEMBL4790157)
Affinity DataIC50:  12nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 2.5 uM measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565053(CHEMBL4790157)
Affinity DataIC50:  12nMAssay Description:Inhibition of ABCB1 in human KB-VIN cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50565054(CHEMBL4783872)
Affinity DataIC50:  14nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 5 uM measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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