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Found 39 with Last Name = 'chen' and Initial = 'is'
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50359989(CHEMBL1927943)
Affinity DataIC50:  300nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reagent methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50353025(CHEMBL1821987)
Affinity DataIC50:  9.59E+3nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as anti-inflammatory activity by measuring maximum inhibition of LPS-induced nitric oxide product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50359990(PRUNETIN)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reagent methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50353027(CHEMBL1821990)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as anti-inflammatory activity by measuring maximum inhibition of LPS-induced nitric oxide product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50359988(CHEMBL1927942)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reagent methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50312648((2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-d...)
Affinity DataIC50:  1.96E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reagent methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50207159(2-aminoguanidine | 2-azanylguanidine | AMINOGUANID...)
Affinity DataIC50:  2.66E+4nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as anti-inflammatory activity by measuring maximum inhibition of LPS-induced nitric oxide product...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50207159(2-aminoguanidine | 2-azanylguanidine | AMINOGUANID...)
Affinity DataIC50:  2.85E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reagent methodMore data for this Ligand-Target Pair
TargetProtein kinase C gamma type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292433(CHEMBL502585 | betulinic acid 3-O-sulfonate potass...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of PKC gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50353026(CHEMBL1821989)
Affinity DataIC50:  3.96E+4nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as anti-inflammatory activity by measuring maximum inhibition of LPS-induced nitric oxide product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50353024(CHEMBL1821986)
Affinity DataIC50:  4.23E+4nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as anti-inflammatory activity by measuring maximum inhibition of LPS-induced nitric oxide product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50353030(CHEMBL1821993)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as anti-inflammatory activity by measuring maximum inhibition of LPS-induced nitric oxide product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292431((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-(3-c...)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of PKC deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50353023(CHEMBL1821985)
Affinity DataIC50:  4.96E+4nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as anti-inflammatory activity by measuring maximum inhibition of LPS-induced nitric oxide product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50353029(CHEMBL1821992)
Affinity DataIC50:  5.14E+4nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as anti-inflammatory activity by measuring maximum inhibition of LPS-induced nitric oxide product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50353028(CHEMBL1821991)
Affinity DataIC50:  5.15E+4nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as anti-inflammatory activity by measuring maximum inhibition of LPS-induced nitric oxide product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50353031(CHEMBL1821994)
Affinity DataIC50:  5.25E+4nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as anti-inflammatory activity by measuring maximum inhibition of LPS-induced nitric oxide product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50353032(CHEMBL1821988)
Affinity DataIC50:  5.82E+4nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as anti-inflammatory activity by measuring maximum inhibition of LPS-induced nitric oxide product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292432(Betulinic acid 3-O-benzoate | CHEMBL509553)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of PKC gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50225106((2S)-2-amino-5-{[(E)-amino(nitroimino)methyl]amino...)
Affinity DataIC50:  1.44E+5nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reagent methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292433(CHEMBL502585 | betulinic acid 3-O-sulfonate potass...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292435((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-((E)...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292432(Betulinic acid 3-O-benzoate | CHEMBL509553)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50103967((3-O-acetyl)betulinic acid | 3-acetylbetulinic aci...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292434(CHEMBL509422 | betulinic acid 28-O-carboxymethylme...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23207((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-5-(hydroxymet...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50103962((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bS)-1-Acet...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50002692((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292431((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-(3-c...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292433(CHEMBL502585 | betulinic acid 3-O-sulfonate potass...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292435((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-((E)...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292432(Betulinic acid 3-O-benzoate | CHEMBL509553)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50103967((3-O-acetyl)betulinic acid | 3-acetylbetulinic aci...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292434(CHEMBL509422 | betulinic acid 28-O-carboxymethylme...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23207((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-5-(hydroxymet...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50103962((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bS)-1-Acet...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292431((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-(3-c...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50002692((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50225106((2S)-2-amino-5-{[(E)-amino(nitroimino)methyl]amino...)
Affinity DataIC50:  1.52E+5nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as anti-inflammatory activity by measuring maximum inhibition of LPS-induced nitric oxide product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed