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Found 311 with Last Name = 'chen' and Initial = 'sb'
TargetAlpha-mannosidase(Canavalia ensiformis)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50579647(CHEMBL5090920)
Affinity DataKi:  17nMAssay Description:Inhibition of Jack bean alpha-mannosidase by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50579646(CHEMBL5078012)
Affinity DataKi:  120nMAssay Description:Inhibition of Jack bean alpha-mannosidase by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHexokinase-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169013(CHEMBL3805703)
Affinity DataKi:  2.90E+3nMAssay Description:Competitive inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) assessed as formation of G6P by continuou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50433027(CHEMBL2375941)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50433028(CHEMBL2375940)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50433018(CHEMBL2375923)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50433019(CHEMBL2375922)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50433022(CHEMBL2375919)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50433005(CHEMBL2375936)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169042(CHEMBL3806103)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169033(CHEMBL3806069)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169038(CHEMBL3804841)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50433026(CHEMBL2375942)
Affinity DataIC50:  8nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50433017(CHEMBL2375924)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169037(CHEMBL3805205)
Affinity DataIC50:  10nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50433004(CHEMBL2375937)
Affinity DataIC50:  12nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50433014(CHEMBL2375927)
Affinity DataIC50:  14nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  14nMAssay Description:Inhibition of equine serum butyrylcholinesterase using butyrylthiocholine chloride as substrate preincubated for 15 mins before substrate addition by...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50433010(CHEMBL2375931)
Affinity DataIC50:  14nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169026(CHEMBL3805148)
Affinity DataIC50:  16nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169032(CHEMBL3805398)
Affinity DataIC50:  20nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  20nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus infected Sf9 insect cells incubated for 50 mins by G...More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetHexokinase-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169037(CHEMBL3805205)
Affinity DataIC50:  20nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50380184(CHEMBL2011200)
Affinity DataIC50:  23nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylcholine chloride as substrate preincubated for 15 mins before substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169041(CHEMBL3805653)
Affinity DataIC50:  25nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169034(CHEMBL3805734)
Affinity DataIC50:  25nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169031(CHEMBL3805905)
Affinity DataIC50:  25nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169038(CHEMBL3804841)
Affinity DataIC50:  25nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592935(CHEMBL5192285)
Affinity DataIC50:  30nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human HDAC8 expressed in baculovirus infected Sf9 insect cells incubated for 50 mins by G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50380183(CHEMBL2011201)
Affinity DataIC50:  31nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylcholine chloride as substrate preincubated for 15 mins before substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169031(CHEMBL3805905)
Affinity DataIC50:  32nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  33nMAssay Description:Inhibition of horse serum butyrylcholinesterase using butylthiocholine as substrate incubated for 15 mins followed by substrate addition measured for...More data for this Ligand-Target Pair
TargetHexokinase-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169039(CHEMBL3806132)
Affinity DataIC50:  40nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169017(CHEMBL3804930)
Affinity DataIC50:  40nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50380187(CHEMBL2011196)
Affinity DataIC50:  41nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylcholine chloride as substrate preincubated for 15 mins before substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50380186(CHEMBL2011202)
Affinity DataIC50:  45nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylcholine chloride as substrate preincubated for 15 mins before substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50380185(CHEMBL2011194)
Affinity DataIC50:  49nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylcholine chloride as substrate preincubated for 15 mins before substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169043(CHEMBL3806095)
Affinity DataIC50:  50nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592937(CHEMBL5195044)
Affinity DataIC50:  50nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHexokinase-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169034(CHEMBL3805734)
Affinity DataIC50:  50nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50433013(CHEMBL2375928)
Affinity DataIC50:  51nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50433016(CHEMBL2375925)
Affinity DataIC50:  56nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50316368(3-(2-N-Pyrrolyl-acetamino)-7,8-dehydrorutaecarpine...)
Affinity DataIC50:  59nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50380182(CHEMBL2011198)
Affinity DataIC50:  60nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylcholine chloride as substrate preincubated for 15 mins before substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592936(CHEMBL5177837)
Affinity DataIC50:  60nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50433015(CHEMBL2375926)
Affinity DataIC50:  64nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  70nMAssay Description:Inhibition of full length recombinant C-terminal GST-tagged human HDAC1 expressed in baculovirus infected Sf9 insect cells incubated for 50 mins by G...More data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592931(CHEMBL5194009)
Affinity DataIC50:  70nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50316369(3-(2-N-Piperidyl-acetamino)-7,8-dehydrorutaecarpin...)
Affinity DataIC50:  70nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50316367(3-(2-Diethylamino-acetamino)-7,8-dehydrorutaecarpi...)
Affinity DataIC50:  70nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine as substrate incubated for 15 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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