Affinity DataIC50: 24nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 203nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 288nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 346nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant Cathepsin S using fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibitory activity was measured against human leukocyte elastase.More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibitory activity was measured against human leukocyte elastase.More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibitory activity was measured against human leukocyte elastase.More data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant Cathepsin L using fluorogenic peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human recombinant Cathepsin B using fluorogenic peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human recombinant Cathepsin K using fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of human recombinant Cathepsin L using fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.20E+4nMAssay Description:Inhibitory activity was measured against trypsin.More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human recombinant Cathepsin C using fluorogenic peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant Cathepsin K using fluorogenic peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human recombinant Cathepsin S using fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibitory activity was measured against thrombin.More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibitory activity was measured against Coagulation factor XMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibitory activity was measured against plasmin.More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibitory activity was measured against thrombin.More data for this Ligand-Target Pair
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibitory activity was measured against trypsin.More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibitory activity was measured against Coagulation factor XMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibitory activity was measured against thrombin.More data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibitory activity was measured against plasmin.More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibitory activity was measured against urokinase.More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibitory activity was measured against urokinase.More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of human recombinant Cathepsin C using fluorogenic peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of human recombinant Cathepsin K using fluorogenic peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of human recombinant Cathepsin B using fluorogenic peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of human recombinant Cathepsin K using fluorogenic peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant Cathepsin K using fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant Cathepsin L using fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant Cathepsin L using fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant Cathepsin L using fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant Cathepsin L using fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by ChEMBL
Novartis Institute For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant Cathepsin L using fluorogenic peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant Cathepsin B using fluorogenic peptide substrateMore data for this Ligand-Target Pair