Affinity DataIC50: 0.200nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 0.251nMAssay Description:Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.501nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.501nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.794nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.794nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.794nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 0.794nMAssay Description:Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of DPP1 in human U937 cells using Gly-Phe-AFC as substrate preincubated for 60 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of radiolabeled iodocyanopindolol from beta1 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of amino methyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whi...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Examples 1-35: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 2.51nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.63nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
Affinity DataIC50: 2.63nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
Affinity DataIC50: 2.82nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 3.16nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 3.16nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 3.16nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of amino methyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whi...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 3.16nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 3.16nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 3.16nMAssay Description:Examples 1-35: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 3.16nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 3.16nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of DPP1 in human U937 cells using Gly-Phe-AFC as substrate preincubated for 60 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Binding affinity to adrenergic beta1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Binding affinity to adrenergic beta1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair