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Found 353 with Last Name = 'costa' and Initial = 'jr'
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
University College London

LigandPNGBDBM181050(3A5)
Affinity DataIC50:  51nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
University College London

LigandPNGBDBM181050(3A5)
Affinity DataIC50:  68nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
University College London

LigandPNGBDBM181052(5F4)
Affinity DataIC50:  127nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
University College London

LigandPNGBDBM181051(5E4)
Affinity DataIC50:  174nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University College London

LigandPNGBDBM181052(5F4)
Affinity DataIC50:  213nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University College London

LigandPNGBDBM181050(3A5)
Affinity DataIC50:  260nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
University College London

LigandPNGBDBM181052(5F4)
Affinity DataIC50:  273nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
University College London

LigandPNGBDBM181051(5E4)
Affinity DataIC50:  277nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University College London

LigandPNGBDBM181051(5E4)
Affinity DataIC50:  334nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
University College London

LigandPNGBDBM181050(3A5)
Affinity DataIC50:  346nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
University College London

LigandPNGBDBM181049(NR9)
Affinity DataIC50:  390nMAssay Description:For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633887(US11807646, Example 301)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633888(US11807646, Example 302)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633889(US11807646, Example 303)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633890(US11807646, Example 304)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633891(US11807646, Example 305)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633892(US11807646, Example 306)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633893(US11807646, Example 307)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633695(US11807646, Example 109)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633696(US11807646, Example 110)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633699(US11807646, Example 113)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633710(5-((7-((R)-3-Cyclohexyl-2- methylpropanoyl)-10-hyd...)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633723(2-((7-((R)-3-Cyclohexyl-2- methylpropanoyl)-10-hyd...)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633729(6-Chloro-3-((7-((R)-3- cyclohexyl-2- methylpropano...)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633737(3-((7-((R)-3-Cyclohexyl-2- methylpropanoyl)-10-hyd...)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633740(3-((7-((R)-3-Cyclohexyl-2- methylpropanoyl)-10-hyd...)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633741(6-Chloro-3-((7-((R)-3- cyclohexyl-2- methylpropano...)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633746(US11807646, Example 160)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633750(US11807646, Example 164)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633751(US11807646, Example 165)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633755(US11807646, Example 169)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633756(US11807646, Example 170)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633757(US11807646, Example 171)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633758(US11807646, Example 172)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633762(US11807646, Example 176)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633764(US11807646, Example 178)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633768(US11807646, Example 182)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633769(US11807646, Example 183)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633770(US11807646, Example 184)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633771(US11807646, Example 185)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633772(US11807646, Example 186)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633773(US11807646, Example 187)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633774(US11807646, Example 188)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633775(US11807646, Example 189)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633776(US11807646, Example 190)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633777(US11807646, Example 191)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633778(US11807646, Example 192)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633779(US11807646, Example 193)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633796(US11807646, Example 210)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 19(Homo sapiens)
Almac Discovery

US Patent
LigandPNGBDBM633797(US11807646, Example 211)
Affinity DataIC50: <500nMAssay Description:Full-length USP19 was purchased from Boston Biochem (E-576). Unless otherwise stated, all other reagents were purchased from Sigma. Enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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