Affinity DataKi: 19nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in Wistar rat cortical membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [3H]-prazosin from alpha1B adrenergic receptor in Wistar rat liver membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 30nM ΔG°: -44.7kJ/mole IC50: 203nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 dopamine receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Binding affinity to 5HT4R (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 dopamine receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Inhibition of Escherichia coli recombinant BPL using 3H-biotin as substrate after 10 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 90nM ΔG°: -41.8kJ/mole IC50: 530nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Displacement of [3H]-RX821002 from alpha2A adrenergic receptor in Wistar rat cortical membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 105nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 dopamine receptor in Wistar rat brain striatal membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Displacement of [3H]-biotin from human BPL after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 dopamine receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 182nMAssay Description:Inhibition of human recombinant BPL using 3H-biotin as substrate after 10 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Displacement of [3H]-biotin from human BPL after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 210nMAssay Description:Displacement of [3H]-OH-8-DPAT from 5HT1A receptor in Wistar rat hippocampal membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 225nM ΔG°: -39.5kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Displacement of [3H]-OH-8-DPAT from 5HT1A receptor in Wistar rat hippocampal membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 283nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 344nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 380nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 dopamine receptor in Wistar rat brain striatal membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 420nM ΔG°: -37.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: 530nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 dopamine receptor in Wistar rat brain striatal membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 563nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 660nM ΔG°: -36.7kJ/mole IC50: 4.00E+3nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 1.15E+3nMAssay Description:Displacement of [3H]-prazosin from alpha1B adrenergic receptor in Wistar rat liver membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.17E+3nM ΔG°: -35.2kJ/mole IC50: 7.00E+3nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: 1.17E+3nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
Affinity DataKi: 1.17E+3nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
Affinity DataKi: 1.83E+3nM ΔG°: -34.1kJ/mole IC50: 1.16E+4nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 2.49E+3nMAssay Description:Displacement of [3H]-RX821002 from alpha2A adrenergic receptor in Wistar rat cortical membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Displacement of [3H]-prazosin from alpha1B adrenergic receptor in Wistar rat liver membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.50E+3nMAssay Description:Displacement of [3H]-biotin from human BPL after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.85E+3nMAssay Description:Displacement of [3H]-biotin from human BPL after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 5.87E+3nMAssay Description:Displacement of [3H]-OH-8-DPAT from 5HT1A receptor in Wistar rat hippocampal membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6.43E+3nMAssay Description:Displacement of [3H]-biotin from human BPL after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 6.45E+3nMAssay Description:Displacement of [3H]-RX821002 from alpha2A adrenergic receptor in Wistar rat cortical membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 6.82E+3nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in Wistar rat cortical membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 8.22E+3nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in Wistar rat cortical membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Universidade Federal De Goi£S
Curated by ChEMBL
Universidade Federal De Goi£S
Curated by ChEMBL
Affinity DataKi: 8.44E+3nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/mole IC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair