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Found 29 with Last Name = 'couch' and Initial = 'rd'
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
George Washington University

Curated by ChEMBL
LigandPNGBDBM50459311(CHEMBL1922604 | FR900098)
Affinity DataIC50:  23nMAssay Description:Inhibition of Plasmodium falciparum DXR assessed as reduction in NADPH oxidation in presence of DOXP by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
George Washington University

Curated by ChEMBL
LigandPNGBDBM50459311(CHEMBL1922604 | FR900098)
Affinity DataIC50:  24nMAssay Description:Inhibition of Plasmodium falciparum DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
George Washington University

Curated by ChEMBL
LigandPNGBDBM50028309(Fosmidomycin Sodium)
Affinity DataIC50:  34nMAssay Description:Inhibition of Plasmodium falciparum DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Dartmouth College

Curated by ChEMBL
LigandPNGBDBM50165429((4aS,6aS,6bR,12aS)-11-Cyano-2,2,6a,6b,9,9,12a-hept...)
Affinity DataIC50:  40nMAssay Description:Inhibition of inducible nitric oxide synthase in activated macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
George Washington University

Curated by ChEMBL
LigandPNGBDBM50028309(Fosmidomycin Sodium)
Affinity DataIC50:  64nMAssay Description:Inhibition of Plasmodium falciparum DXR assessed as reduction in NADPH oxidation in presence of DOXP by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
George Washington University

Curated by ChEMBL
LigandPNGBDBM50459310(CHEMBL4207168)
Affinity DataIC50:  92nMAssay Description:Inhibition of Plasmodium falciparum DXR assessed as reduction in NADPH oxidation in presence of DOXP by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50380000(CHEMBL258981)
Affinity DataIC50:  159nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081647(CHEMBL3422252)
Affinity DataIC50:  205nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
George Washington University

Curated by ChEMBL
LigandPNGBDBM50445564(CHEMBL3103256)
Affinity DataIC50:  206nMAssay Description:Inhibition of Plasmodium falciparum DXR assessed as reduction in NADPH oxidation in presence of DOXP by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)
Affinity DataIC50:  438nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)
Affinity DataIC50:  440nMAssay Description:Inhibition of Mycobacterium tuberculosis DxrMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Dartmouth College

Curated by ChEMBL
LigandPNGBDBM50165431((4aS,6aS,6bR,12aR)-11-Cyano-2,2,6a,6b,9,9,12a-hept...)
Affinity DataIC50:  600nMAssay Description:Inhibition of inducible nitric oxide synthase in activated macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081649(CHEMBL3422255)
Affinity DataIC50:  843nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50445564(CHEMBL3103256)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DxrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50380000(CHEMBL258981)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
George Washington University

Curated by ChEMBL
LigandPNGBDBM50459307(CHEMBL4215008)
Affinity DataIC50:  2.11E+3nMAssay Description:Inhibition of Plasmodium falciparum DXR assessed as reduction in NADPH oxidation in presence of DOXP by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)
Affinity DataIC50:  2.39E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DxrMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
George Washington University

Curated by ChEMBL
LigandPNGBDBM50459312(CHEMBL4210088)
Affinity DataIC50:  2.54E+3nMAssay Description:Inhibition of Plasmodium falciparum DXR assessed as reduction in NADPH oxidation in presence of DOXP by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Dartmouth College

Curated by ChEMBL
LigandPNGBDBM50165436((4aS,6aR,6bR,12aR)-2,2,6a,6b,9,9,12a-Heptamethyl-1...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of inducible nitric oxide synthase in activated macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
George Washington University

Curated by ChEMBL
LigandPNGBDBM50459308(CHEMBL4202817)
Affinity DataIC50:  4.53E+3nMAssay Description:Inhibition of Plasmodium falciparum DXR assessed as reduction in NADPH oxidation in presence of DOXP by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Dartmouth College

Curated by ChEMBL
LigandPNGBDBM50165432((4aS,6aS,6bR,12aR)-2,2,6a,6b,9,9,12a-Heptamethyl-1...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of inducible nitric oxide synthase in activated macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081650(CHEMBL3422256)
Affinity DataIC50:  6.67E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081647(CHEMBL3422252)
Affinity DataIC50:  7.13E+3nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081649(CHEMBL3422255)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
George Washington University

Curated by ChEMBL
LigandPNGBDBM50459309(CHEMBL4211531)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of Plasmodium falciparum DXR assessed as reduction in NADPH oxidation in presence of DOXP by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081648(CHEMBL3422254)
Affinity DataIC50:  3.14E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Dartmouth College

Curated by ChEMBL
LigandPNGBDBM50346613(CHEMBL470029 | Oleanonic Acid)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of inducible nitric oxide synthase in activated macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Dartmouth College

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of inducible nitric oxide synthase in activated macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081650(CHEMBL3422256)
Affinity DataIC50:  2.73E+5nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed