TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Chiron
Curated by ChEMBL
Chiron
Curated by ChEMBL
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Chiron
Curated by ChEMBL
Chiron
Curated by ChEMBL
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Chiron
Curated by ChEMBL
Chiron
Curated by ChEMBL
Affinity DataIC50: >1nMAssay Description:Inhibition of CamK2alphaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of AKT3 in presence of 0.2 uM ATPMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of AKT3 in presence of 0.2 uM ATPMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of AKT3 in presence of 0.2 uM ATPMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of AKT3 in presence of 0.2 uM ATPMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 18.4nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of AKT3 in presence of 0.2 uM ATPMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of PI3K p110alpha subunit using [gamma33P]ATP by filter binding assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphotidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:Inhibition of PI3K p110delta subunit using [gamma33P]ATP by filter binding assayMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Chiron
Curated by ChEMBL
Chiron
Curated by ChEMBL
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 142nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 166nMAssay Description:Inhibition of PI3K p110beta subunit using [gamma33P]ATP by filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of AKT3 in presence of 0.2 uM ATPMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 262nMAssay Description:Inhibition of PI3K p110gamma subunit using [gamma33P]ATP by filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of AKT3 in presence of 0.2 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Inhibition of AKT3 in presence of 0.2 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Inhibition of AKT3 in presence of 0.2 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Inhibition of AKT3 in presence of 0.2 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 990nMAssay Description:Inhibition of AKT3 in presence of 0.2 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of AKT3 in presence of 0.2 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MetMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of AKT3 in presence of 0.2 uM ATPMore data for this Ligand-Target Pair