Affinity DataKi: 0.360nMAssay Description:Binding affinity to BRS-3 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.990nMAssay Description:Binding affinity to gastrin releasing peptide receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 8.90nMAssay Description:Binding affinity to neuromedin B receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 174nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.59E+3nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 2.95E+3nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 3.16E+3nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 3.98E+3nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor (unknown origin) expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mo...More data for this Ligand-Target Pair
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor (unknown origin) expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mo...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+3nMAssay Description:Agonist activity at recombinant BRS-3 receptor (unknown origin) expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mo...More data for this Ligand-Target Pair
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor (unknown origin) expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mo...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor (unknown origin) expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mo...More data for this Ligand-Target Pair
Affinity DataEC50: >3.20E+4nMAssay Description:Agonist activity at recombinant BRS-3 receptor (unknown origin) expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mo...More data for this Ligand-Target Pair