TargetAromatase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as tritiated water release after 15 mins using [1beta, 3H]androstenedione as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in 6-beta-hydroxy-testosterone formation using testosterone as substrate preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in 1'-hydroxy midazolam formation using midazolam as substrate preincubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in 6-beta-hydroxy-testosterone formation using testosterone as substrate preincu...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of hERG channel expressed in CHO cells at holding potential of -80 mV by whole cell patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in 1'-hydroxy midazolam formation using midazolam as substrate preincubated for ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of hERG channel expressed in CHO cells at holding potential of -80 mV by whole cell patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of hERG channel expressed in CHO cells at holding potential of -80 mV by whole cell patch clamp methodMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as tritiated water release after 15 mins using [1beta, 3H]androstenedione as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in 6-beta-hydroxy-testosterone formation using testosterone as substrate preincu...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of hERG channel expressed in CHO cells at holding potential of -80 mV by whole cell patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of hERG channel expressed in CHO cells at holding potential of -80 mV by whole cell patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of hERG channel expressed in CHO cells at holding potential of -80 mV by whole cell patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in 6-beta-hydroxy-testosterone formation using testosterone as substrate preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in 6-beta-hydroxy-testosterone formation using testosterone as substrate preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in 6-beta-hydroxy-testosterone formation using testosterone as substrate preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in 1'-hydroxy midazolam formation using midazolam as substrate preincubated for ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hERG channel expressed in CHO cells at holding potential of -80 mV by whole cell patch clamp methodMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as tritiated water release after 15 mins using [1beta, 3H]androstenedione as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in 1'-hydroxy midazolam formation using midazolam as substrate preincubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in 1'-hydroxy midazolam formation using midazolam as substrate preincubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in 1'-hydroxy midazolam formation using midazolam as substrate preincubated for ...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as tritiated water release after 15 mins using [1beta, 3H]androstenedione as substrate...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as tritiated water release after 15 mins using [1beta, 3H]androstenedione as substrate...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as tritiated water release after 15 mins using [1beta, 3H]androstenedione as substrate...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as tritiated water release after 15 mins using [1beta, 3H]androstenedione as substrate...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as tritiated water release after 15 mins using [1beta, 3H]androstenedione as substrate...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as tritiated water release after 15 mins using [1beta, 3H]androstenedione as substrate...More data for this Ligand-Target Pair
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Affinity DataIC50: 5.25E+6nMAssay Description:Inhibition of beta-hematin formationMore data for this Ligand-Target Pair
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Affinity DataIC50: 5.90E+6nMAssay Description:Inhibition of beta-hematin formationMore data for this Ligand-Target Pair
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Affinity DataIC50: >2.00E+7nMAssay Description:Inhibition of beta-hematin formationMore data for this Ligand-Target Pair
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Affinity DataIC50: >2.00E+7nMAssay Description:Inhibition of beta-hematin formationMore data for this Ligand-Target Pair
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Universidade Federal Do Rio Grande Do Sul (Ufrgs)
Curated by ChEMBL
Affinity DataIC50: >2.00E+7nMAssay Description:Inhibition of beta-hematin formationMore data for this Ligand-Target Pair