Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.60nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.20nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 10.2nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 10.6nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 10.7nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 10.8nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 11.8nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 15.2nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 15.9nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 20.3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 23.2nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 25.5nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 30.1nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 30.2nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 30.5nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 55.3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 63.5nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 82.3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 127nM ΔG°: -40.9kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (6080 Ci/mmol), respectively. The ...More data for this Ligand-Target Pair
Affinity DataKi: 303nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 464nM ΔG°: -37.6kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (6080 Ci/mmol), respectively. The ...More data for this Ligand-Target Pair
Affinity DataKi: >500nM ΔG°: >-37.4kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (6080 Ci/mmol), respectively. The ...More data for this Ligand-Target Pair
Affinity DataKi: 536nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 586nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 682nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Suven Life Sciences
Curated by ChEMBL
Suven Life Sciences
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Displacement of [3H]astemizole from human ERG by microbeta scintillation countingMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Suven Life Sciences
Curated by ChEMBL
Suven Life Sciences
Curated by ChEMBL
Affinity DataKi: 950nMAssay Description:Displacement of [3H]astemizole from human ERG by microbeta scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 955nMAssay Description:Binding affinity to adrenergic alpha1B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.81E+3nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Suven Life Sciences
Curated by ChEMBL
Suven Life Sciences
Curated by ChEMBL
Affinity DataKi: 1.94E+3nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
Affinity DataKi: 1.96E+3nMAssay Description:Binding affinity to 5HT7 receptorMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Suven Life Sciences
Curated by ChEMBL
Suven Life Sciences
Curated by ChEMBL
Affinity DataKi: 2.01E+3nMAssay Description:Binding affinity to NOR transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Suven Life Sciences
Curated by ChEMBL
Suven Life Sciences
Curated by ChEMBL
Affinity DataKi: 2.13E+3nMAssay Description:Binding affinity to NOR transporterMore data for this Ligand-Target Pair
Affinity DataKi: 2.24E+3nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.37E+3nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Suven Life Sciences
Curated by ChEMBL
Suven Life Sciences
Curated by ChEMBL
Affinity DataKi: 2.90E+3nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 3.12E+3nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Suven Life Sciences
Curated by ChEMBL
Suven Life Sciences
Curated by ChEMBL
Affinity DataKi: 3.22E+3nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 3.79E+3nMAssay Description:Binding affinity to adrenergic alpha1B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.37E+3nMAssay Description:Binding affinity to 5HT7 receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Suven Life Sciences
Curated by ChEMBL
Suven Life Sciences
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]astemizole from human ERG by microbeta scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Suven Life Sciences
Curated by ChEMBL
Suven Life Sciences
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
Affinity DataIC50: 292nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
Affinity DataIC50: 322nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
Affinity DataIC50: 1.53E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
Affinity DataIC50: 1.78E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 5 mins by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair