TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute Of Chemical Biology
Curated by ChEMBL
Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 1.01nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brainMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Institute Of Chemical Biology
Curated by ChEMBL
Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 1.03nMAssay Description:Displacement of [3H]dynorphin from human kappa opioid receptor expressed in C6 giloma cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute Of Chemical Biology
Curated by ChEMBL
Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 1.15nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brainMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Institute Of Chemical Biology
Curated by ChEMBL
Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 1.99nMAssay Description:Displacement of [3H]dynorphin from human kappa opioid receptor expressed in C6 giloma cellsMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132G](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 2.90nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 3.80nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 4.60nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 46nMT: 2°CAssay Description:For WT IDH1 and IDH2, reactions were conducted at room temperature in 384-well Greiner black microtiter plates in a total volume of 10 μL of ass...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 496nMT: 2°CAssay Description:For WT IDH1 and IDH2, reactions were conducted at room temperature in 384-well Greiner black microtiter plates in a total volume of 10 μL of ass...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP], mitochondrial [R172S](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 1.03E+3nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP], mitochondrial [R140Q](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 1.36E+3nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 4.50E+3nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 1.09E+4nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132G](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 2.33E+4nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP], mitochondrial [R172S](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:For WT IDH1 and IDH2, reactions were conducted at room temperature in 384-well Greiner black microtiter plates in a total volume of 10 μL of ass...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:For WT IDH1 and IDH2, reactions were conducted at room temperature in 384-well Greiner black microtiter plates in a total volume of 10 μL of ass...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP], mitochondrial [R140Q](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair