Compile Data Set for Download or QSAR
maximum 50k data
Found 42 with Last Name = 'dempsey' and Initial = 'e'
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344448(2-(1-(4-chlorobenzyl)-1H-benzo[d]imidazol-2-ylthio...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344444(3-amino-4-(4-(benzyloxy)-3-methoxyphenyl)-N-(5-chl...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344447(CHEMBL1780016 | methyl-5-(diethylcarbamoyl)-4-meth...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344449(CHEMBL1780018 | ethyl 4-(5-(4-tert-butylbenzyliden...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344450(1-(benzo[d][1,3]dioxol-5-ylmethyl)-1-((8-methyl-2-...)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344446(CHEMBL1699130 | dimethyl-4,4'-(ethane-1,2-diylbis(...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344445(CHEMBL1780014 | N-(3-(1-(2-(2-(3-butoxyphenyl)quin...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344451((S)-N5-(1-(1H-indol-3-yl)-2-(isopentylamino)-2-oxo...)
Affinity DataKi:  1.06E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054486(CHEMBL141424 | N-[(S)-1-((S)-1-Carbamimidoyl-piper...)
Affinity DataIC50:  0.670nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054484(CHEMBL344204 | CVS-1778 | N-((S)-1-Formyl-4-guanid...)
Affinity DataIC50:  0.710nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054482((S)-4-[(S)-2-((S)-1-Formyl-4-guanidino-butylcarbam...)
Affinity DataIC50:  1.20nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054482((S)-4-[(S)-2-((S)-1-Formyl-4-guanidino-butylcarbam...)
Affinity DataIC50:  1.20nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054483((S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-y...)
Affinity DataIC50:  1.70nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054483((S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-y...)
Affinity DataIC50:  1.70nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataIC50:  1.80nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataIC50:  1.80nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054488(CHEMBL138441 | CVS-1178 | N-((S)-1-Formyl-4-guanid...)
Affinity DataIC50:  12.4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054484(CHEMBL344204 | CVS-1778 | N-((S)-1-Formyl-4-guanid...)
Affinity DataIC50:  20.6nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054485(CHEMBL342604 | N-[(S)-1-((R)-1-Carbamimidoyl-piper...)
Affinity DataIC50:  28.8nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054483((S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-y...)
Affinity DataIC50:  113nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054483((S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-y...)
Affinity DataIC50:  113nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054482((S)-4-[(S)-2-((S)-1-Formyl-4-guanidino-butylcarbam...)
Affinity DataIC50:  301nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054484(CHEMBL344204 | CVS-1778 | N-((S)-1-Formyl-4-guanid...)
Affinity DataIC50:  329nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054488(CHEMBL138441 | CVS-1178 | N-((S)-1-Formyl-4-guanid...)
Affinity DataIC50:  1.55E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344444(3-amino-4-(4-(benzyloxy)-3-methoxyphenyl)-N-(5-chl...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344448(2-(1-(4-chlorobenzyl)-1H-benzo[d]imidazol-2-ylthio...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataIC50: >2.50E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054488(CHEMBL138441 | CVS-1178 | N-((S)-1-Formyl-4-guanid...)
Affinity DataIC50: >2.50E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataIC50: >2.50E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344447(CHEMBL1780016 | methyl-5-(diethylcarbamoyl)-4-meth...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054483((S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-y...)
Affinity DataIC50: >2.50E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344449(CHEMBL1780018 | ethyl 4-(5-(4-tert-butylbenzyliden...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344450(1-(benzo[d][1,3]dioxol-5-ylmethyl)-1-((8-methyl-2-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344446(CHEMBL1699130 | dimethyl-4,4'-(ethane-1,2-diylbis(...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344445(CHEMBL1780014 | N-(3-(1-(2-(2-(3-butoxyphenyl)quin...)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataIC50:  1.51E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataIC50:  1.51E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344451((S)-N5-(1-(1H-indol-3-yl)-2-(isopentylamino)-2-oxo...)
Affinity DataIC50:  2.13E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054485(CHEMBL342604 | N-[(S)-1-((R)-1-Carbamimidoyl-piper...)
Affinity DataIC50: >2.50E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054486(CHEMBL141424 | N-[(S)-1-((S)-1-Carbamimidoyl-piper...)
Affinity DataIC50: >2.50E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054485(CHEMBL342604 | N-[(S)-1-((R)-1-Carbamimidoyl-piper...)
Affinity DataIC50:  6.07E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054486(CHEMBL141424 | N-[(S)-1-((S)-1-Carbamimidoyl-piper...)
Affinity DataIC50:  6.48E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed