Affinity DataKi: 900nM ΔG°: -35.9kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nM ΔG°: -34.9kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nM ΔG°: -33.5kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nM ΔG°: -32.2kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 5.40E+3nM ΔG°: -31.3kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 1.92E+4nM ΔG°: -28.0kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nM ΔG°: -27.9kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nM ΔG°: -25.8kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 5.60E+4nM ΔG°: -25.2kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 1.37E+5nM ΔG°: -22.9kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Kingston University
Curated by ChEMBL
Kingston University
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Compound was tested for the inhibitory activity against Steroid 5-alpha-reductase in ratMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rattus norvegicus)
Kingston University
Curated by ChEMBL
Kingston University
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Compound was tested for the inhibitory activity against Steroid 5-alpha-reductase type 1 in ratMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Kingston University
Curated by ChEMBL
Kingston University
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Compound was tested for the inhibitory activity against Steroid 5-alpha-reductase in ratMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against COX2 in feline whole blood assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Kingston University
Curated by ChEMBL
Kingston University
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Compound was tested for the inhibitory activity against Steroid 5-alpha-reductase in ratMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 125nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 132nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 197nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 297nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair