Found 1089 with Last Name = 'devraj' and Initial = 'r' 
Affinity DataKi: 2.90nMAssay Description:Inhibition of p38alpha kinaseMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 6nMAssay Description:Inhibition of p38beta kinaseMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of p38beta kinaseMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of p38beta kinaseMore data for this Ligand-Target Pair
Affinity DataKi: 193nMAssay Description:Inhibition of p38alpha kinaseMore data for this Ligand-Target Pair
Affinity DataKi: >4.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of CCR2-mediated Erk phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibitory concentration of the compound against CCRF-CEM leukemic cell DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 0.850nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Toxoplasma gondii (tg)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of p38alpha assessed as phosphorylation of fluorescently-labelled MK2 using Hsp27 peptide as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration of the compound for DHFR in Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Rat liver (rl)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at CCR2 receptor in human PBMC assessed as inhibition of MCP1-mediated leukocyte chemotaxis after 30 mins by microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at CCR2 receptor in human PBMC assessed as inhibition of MCP1-mediated leukocyte chemotaxis after 30 mins by microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of p38alpha assessed as phosphorylation of fluorescently-labelled MK2 using Hsp27 peptide as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of p38alpha assessed as phosphorylation FITC-labeled Hsp27 after 60 mins by fluorescence based cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of p38alpha assessed as phosphorylation FITC-labeled Hsp27 after 60 mins by fluorescence based cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of p38alpha assessed as phosphorylation FITC-labeled Hsp27 after 60 mins by fluorescence based cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of p38alpha assessed as phosphorylation FITC-labeled Hsp27 after 60 mins by fluorescence based cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity at CCR2 receptor in human PBMC assessed as inhibition of MCP1-mediated leukocyte chemotaxis after 30 mins by microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Antagonist activity at rat CCR2More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Binding affinity to mouse CCR2More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 1 hrs by human whole cell binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Binding affinity to rat CCR2More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Rat liver (rl)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of p38alpha assessed as phosphorylation FITC-labeled Hsp27 after 60 mins by fluorescence based cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated for 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of p38alpha assessed as phosphorylation of fluorescently-labelled MK2 using Hsp27 peptide as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of p38alpha assessed as phosphorylation of fluorescently-labelled MK2 using Hsp27 peptide as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 by human whole cell binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration of the compound for DHFR in rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1-induced chemotaxis by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of MCP-Alexa 488 from CCR2 in human whole blood after 5 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 in PBMC after 30 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 in PBMC after 30 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of CCR2-mediated calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at CCR2 receptor in human PBMC assessed as inhibition of MCP1-mediated leukocyte chemotaxis after 30 mins by microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Displacement of [125I]MCP1 from human CCR2 in PBMC after 30 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]MCP1 from human CCR2 in PBMC after 30 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity at CCR2 receptor in human PBMC assessed as inhibition of MCP1-mediated leukocyte chemotaxis after 30 mins by microscopyMore data for this Ligand-Target Pair
