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Found 551 with Last Name = 'donovan' and Initial = 'a'
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataKi:  1nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513361(CHEMBL4567766)
Affinity DataKi:  1nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513360(CHEMBL4573390)
Affinity DataKi:  2nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataKi:  2nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50151923(CHEMBL3774537)
Affinity DataKi:  2nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50151923(CHEMBL3774537)
Affinity DataKi:  3nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataKi:  3nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513361(CHEMBL4567766)
Affinity DataKi:  3nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataKi:  4nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataKi:  4nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513348(CHEMBL4585876)
Affinity DataKi:  4nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513348(CHEMBL4585876)
Affinity DataKi:  4nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513360(CHEMBL4573390)
Affinity DataKi:  5nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataKi:  7nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513346(CHEMBL4525269)
Affinity DataKi:  16nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513346(CHEMBL4525269)
Affinity DataKi:  26nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24828(Brassinin derivative, 16 | N-[2-(1H-indol-3-yl)eth...)
Affinity DataKi:  1.16E+4nM ΔG°:  -29.3kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24825((benzylsulfanyl)-N-(1H-indol-3-ylmethyl)carbothioa...)
Affinity DataKi:  1.32E+4nM ΔG°:  -29.0kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24827((benzylsulfanyl)-N-[2-(1H-indol-3-yl)ethyl]carboth...)
Affinity DataKi:  1.72E+4nM ΔG°:  -28.3kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24830(Brassinin derivative, 18 | N-[2-(1H-indol-3-yl)eth...)
Affinity DataKi:  2.05E+4nM ΔG°:  -27.8kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24829(Brassinin derivative, 17 | N-[2-(1H-indol-3-yl)eth...)
Affinity DataKi:  2.84E+4nM ΔG°:  -27.0kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24816(Brassinin derivative, 4 | N-[3-(1H-indol-3-yl)prop...)
Affinity DataKi:  3.40E+4nM ΔG°:  -26.5kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24824(Brassinin derivative, 12 | N-(1H-indol-3-ylmethyl)...)
Affinity DataKi:  3.70E+4nM ΔG°:  -26.3kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24815(Brassinin derivative, 3 | N-[2-(1-benzothiophen-3-...)
Affinity DataKi:  4.10E+4nM ΔG°:  -26.1kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24817(Brassinin derivative, 5 | N-(2,3-dihydro-1H-inden-...)
Affinity DataKi:  4.21E+4nM ΔG°:  -26.0kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24819((methylsulfanyl)-N-(naphthalen-2-ylmethyl)carbothi...)
Affinity DataKi:  4.76E+4nM ΔG°:  -25.7kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24821((methylsulfanyl)-N-(2-phenylethyl)carbothioamide |...)
Affinity DataKi:  6.24E+4nM ΔG°:  -25.0kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24820(Brassinin derivative, 8 | N-benzyl(methylsulfanyl)...)
Affinity DataKi:  7.24E+4nM ΔG°:  -24.6kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24814(Brassinin derivative, 2 | N-[2-(1H-indol-3-yl)ethy...)
Affinity DataKi:  8.25E+4nM ΔG°:  -24.2kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24813(Brassinin, 1 | N-(1H-indol-3-ylmethyl)(methylsulfa...)
Affinity DataKi:  9.77E+4nM ΔG°:  -23.8kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24822(Brassinin derivative, 10 | N-[2-(4-fluorophenyl)et...)
Affinity DataKi:  1.49E+5nM ΔG°:  -22.7kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24818(Brassinin derivative, 6 | N-(adamantan-2-yl)(methy...)
Affinity DataKi:  1.80E+5nM ΔG°:  -22.2kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24834(N-(1H-indol-3-ylmethyl)propanethioamide | thioamid...)
Affinity DataKi:  2.02E+5nM ΔG°:  -21.9kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24836(4-(1H-indol-3-ylmethyl)-2-methyl-1,3-thiazole | th...)
Affinity DataKi:  3.29E+5nM ΔG°:  -20.7kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24832(1-[2-(1H-indol-3-yl)ethyl]-3-methylthiourea | thio...)
Affinity DataKi:  3.42E+5nM ΔG°:  -20.6kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24826((hexylsulfanyl)-N-(1H-indol-3-ylmethyl)carbothioam...)
Affinity DataKi:  3.64E+5nM ΔG°:  -20.4kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24823(Brassinin derivative, 11 | N-methyl(methylsulfanyl...)
Affinity DataKi:  1.27E+6nM ΔG°:  -17.2kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24835(4-(1H-indol-3-ylmethyl)-1,3-thiazole | thiazole, 2...)
Affinity DataKi:  1.29E+6nM ΔG°:  -17.2kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50:  4nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50:  5nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50:  5nMAssay Description:Inhibition of full length human KDM5B assessed as decrease in demethylation of substrate using peptide ARTK(me3)QTARKSTGGKAPRKQLA-GGK-biotin as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50:  6nMAssay Description:Inhibition of KDM5B (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50:  6nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50:  7nMAssay Description:Inhibition of full length human KDM5B assessed as decrease in demethylation of substrate using peptide ARTK(me3)QTARKSTGGKAPRKQLA-GGK-biotin as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153099(CHEMBL3775814)
Affinity DataIC50:  7nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50:  8nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50:  8nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50:  8nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50:  9nMAssay Description:Inhibition of full length human KDM5B assessed as decrease in demethylation of substrate using peptide ARTK(me3)QTARKSTGGKAPRKQLA-GGK-biotin as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153101(CHEMBL3774665)
Affinity DataIC50:  10nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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