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Found 347 with Last Name = 'doodeman' and Initial = 'r'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332053(US10189854, Compound 1 | [1-[5-(2-Fluorophenyl)-py...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332054(1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]-N,N-dimethyl...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332055(US10189854, Compound 3 | [1-[5-(1-Fluorophenyl)-py...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332056(4-[1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]-spiro[1,2...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332057(US10189854, Compound 5 | [1-[5-(2-Fluorophenyl)-py...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332059(Morpholin-4-yl-[1-(5-phenyl-pyrimidin-2-yl)-spiro[...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332060(US10189854, Compound 8 | [1-[5-(2,4-Difluoro-pheny...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332062(Morpholin-4-yl-[1-(5-o-tolyl-pyrimidin-2-yl)-spiro...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332063(US10189854, Compound 15 | [1-[5-(2,3-Difluoro-phen...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332064(US10189854, Compound 16 | [1-[5-(2-Fluoro-5-methox...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332065(US10189854, Compound 17 | [1-[5-(2-Fluoro-4-methox...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332070(4-Fluoro-3-[2-[6-(morpholine-4-carbonyl)-spiro[1,2...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332071(US10189854, Compound 23 | [1-[5-[2-Fluoro-5-(trifl...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332074(3-Fluoro-4-[2-[6-(morpholine-4-carbonyl)-spiro[1,2...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332075(US10189854, Compound 27 | [1-[5-(2,6-Difluoro-phen...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332077(US10189854, Compound 29 | [1-[5-(2-Fluoro-4-methyl...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332079(US10189854, Compound 31 | [1-[5-(2-Methoxyphenyl)-...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332081(US10189854, Compound 34 | US10189854, Compound 94 ...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332082(4-Fluoro-3-[2-[6-(morpholine-4-carbonyl)-spiro[1,2...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332084(4-[1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]spiro[1,2-...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332086(US10189854, Compound 40 | [(3R)-3-Amino-pyrrolidin...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332087(N-(2-Amino-ethyl)-1-[5-(2-fluorophenyl)-pyrimidin-...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332088(US10189854, Compound 42 | [1-[5-(2-Fluoro-5-methyl...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332089(US10189854, Compound 43 | [1-[5-(4-Fluorophenyl)-p...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332090(US10189854, Compound 44 | [1-[5-(2-Fluorophenyl)-p...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332094(US10189854, Compound 48 | [1-[5-(3-Methoxyphenyl)-...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332095(US10189854, Compound 49 | [1-(5-Phenyl-pyrimidin-2...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332096(US10189854, Compound 50 | [1-[5-(3,5-Difluoro-phen...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332098(US10189854, Compound 52 | [1-[5-(2-Fluoro-5-methyl...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332100(3-[2-[6-(Morpholine-4-carbonyl)-spiro[1,2-dihydro-...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332101(4-[1-(5-Phenyl-pyrimidin-2-yl)-spiro[1,2-dihydro-i...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332102(3-[2-[6-(Morpholine-4-carbonyl)-spiro[1,2-dihydro-...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332103(US10189854, Compound 57 | [1-[5-(3-Fluorophenyl)-p...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332104(US10189854, Compound 58 | [1-[5-(5-Chloro-2-fluoro...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332105(US10189854, Compound 59 | [1-(5-Phenyl-pyrimidin-2...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332106(US10189854, Compound 60 | [1-[5-(2-Fluorophenyl)-p...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332109(4-[2-[6-(Morpholine-4-carbonyl)-spiro[1,2-dihydro-...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332111(3-Fluoro-N,N-dimethyl-4-[2-[6-(morpholine-4-carbon...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332118(US10189854, Compound 72 | [1-[5-[2-Fluoro-5-(trifl...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332119(US10189854, Compound 73 | [1-[5-(2-Fluoro-5-methox...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332128(US10189854, Compound 84 | [1-[5-(2-Fluorophenyl)-p...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332129(1-[5-[1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]-spiro[...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332137(US10189854, Compound 93 | [1-[5-(2-Fluorophenyl)-p...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332081(US10189854, Compound 34 | US10189854, Compound 94 ...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332139(1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]-N-(2-hydroxy...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332140(US10189854, Compound 96 | [1-[5-(2-Fluorophenyl)-p...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332143(N-[2-(Dimethylamino)ethyl]-1-[5-(2-fluorophenyl)-p...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332147(US10189854, Compound 103 | [1-[5-(2-Fluorophenyl)-...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332148(US10189854, Compound 104 | [(2R,6S)-2,6-dimethyl-m...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332151((2,5-Diazabicyclo[2.2.1]heptan-2-yl)-[1-[5-(2-fluo...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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