Affinity DataKi: 2.20E+4nMAssay Description:Noncompetitive inhibition of human granulocyte elastase using Ac-Ala-Ala-Pro-Ala-p-nitroanilide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+4nMAssay Description:Noncompetitive inhibition of human granulocyte elastase using Ac-Ala-Ala-Pro-Ala-p-nitroanilide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.80E+4nMAssay Description:Noncompetitive inhibition of human granulocyte elastase using Ac-Ala-Ala-Pro-Ala-p-nitroanilide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+4nMAssay Description:Noncompetitive inhibition of human granulocyte elastase using Ac-Ala-Ala-Pro-Ala-p-nitroanilide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+4nMAssay Description:Noncompetitive inhibition of human granulocyte elastase using Ac-Ala-Ala-Pro-Ala-p-nitroanilide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+4nMAssay Description:Noncompetitive inhibition of human granulocyte elastase using Ac-Ala-Ala-Pro-Ala-p-nitroanilide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:compounds were evaluated for inhibitory activity against human Tachykinin receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligand at a concentration of 1000 ...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligand at a concentration of 1000 ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of Prostaglandin G/H synthase of ram seminal vesicle microsomesMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of Prostaglandin G/H synthase of ram seminal vesicle microsomesMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 217nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 267nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair