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Found 29 with Last Name = 'doshi' and Initial = 'jm'
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi:  188nMAssay Description:Inhibition of recombinant His6-tagged Bcl-XL expressed in Escherichia coli BL21 (DE3) and Flu-Bak peptide interaction by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataKi:  6.54E+3nMAssay Description:Inhibition of recombinant His6-tagged MCL1 (171-326) expressed in Escherichia coli BL21 (DE3) and Flu-Bak peptide interaction by fluorescence polariz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200960(CHEMBL216089 | ethyl 2-amino-6-(4-tert-butylphenyl...)
Affinity DataKi:  2.03E+4nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200960(CHEMBL216089 | ethyl 2-amino-6-(4-tert-butylphenyl...)
Affinity DataKi:  2.17E+4nMAssay Description:Binding affinity to BclXL by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200964(CHEMBL219234 | ethyl 2-amino-6-cyclopentyl-4-(1-cy...)
Affinity DataKi:  3.08E+4nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200964(CHEMBL219234 | ethyl 2-amino-6-cyclopentyl-4-(1-cy...)
Affinity DataKi:  3.65E+4nMAssay Description:Binding affinity to BclXL by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200962(CHEMBL219366 | ethyl 2-amino-6-phenyl-4-(1-cyano-2...)
Affinity DataKi:  4.12E+4nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200962(CHEMBL219366 | ethyl 2-amino-6-phenyl-4-(1-cyano-2...)
Affinity DataKi:  5.29E+4nMAssay Description:Binding affinity to BclXL by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200963(CHEMBL425792 | ethyl 2-amino-6-n-propyl-4-(1-cyano...)
Affinity DataKi:  5.67E+4nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50024671(CHEMBL2374449)
Affinity DataKi:  5.89E+4nMAssay Description:Binding affinity to BclXL by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50024671(CHEMBL2374449)
Affinity DataKi:  5.93E+4nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200963(CHEMBL425792 | ethyl 2-amino-6-n-propyl-4-(1-cyano...)
Affinity DataKi:  7.07E+4nMAssay Description:Binding affinity to BclXL by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200962(CHEMBL219366 | ethyl 2-amino-6-phenyl-4-(1-cyano-2...)
Affinity DataKi:  1.12E+5nMAssay Description:Binding affinity to Bcl2 by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200961(CHEMBL384519 | ethyl 2-amino-6-ethyl-4-(1-cyano-2-...)
Affinity DataKi:  1.21E+5nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200963(CHEMBL425792 | ethyl 2-amino-6-n-propyl-4-(1-cyano...)
Affinity DataKi:  1.28E+5nMAssay Description:Binding affinity to Bcl2 by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200964(CHEMBL219234 | ethyl 2-amino-6-cyclopentyl-4-(1-cy...)
Affinity DataKi:  1.28E+5nMAssay Description:Binding affinity to Bcl2 by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200961(CHEMBL384519 | ethyl 2-amino-6-ethyl-4-(1-cyano-2-...)
Affinity DataKi:  1.35E+5nMAssay Description:Binding affinity to BclXL by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50024671(CHEMBL2374449)
Affinity DataKi:  1.69E+5nMAssay Description:Binding affinity to Bcl2 by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200967(CHEMBL220350 | ethyl 2-amino-6-methyl-4-(1-cyano-2...)
Affinity DataKi:  1.91E+5nMAssay Description:Binding affinity to BclXL by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200967(CHEMBL220350 | ethyl 2-amino-6-methyl-4-(1-cyano-2...)
Affinity DataKi:  1.99E+5nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200961(CHEMBL384519 | ethyl 2-amino-6-ethyl-4-(1-cyano-2-...)
Affinity DataKi:  2.10E+5nMAssay Description:Binding affinity to Bcl2 by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200967(CHEMBL220350 | ethyl 2-amino-6-methyl-4-(1-cyano-2...)
Affinity DataKi:  3.09E+5nMAssay Description:Binding affinity to Bcl2 by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297392(CHEMBL560141 | ethyl 2-amino-4-(2-ethoxy-2-oxoethy...)
Affinity DataKi:  3.44E+5nMAssay Description:Inhibition of recombinant His6-tagged Bcl-XL expressed in Escherichia coli BL21 (DE3) and Flu-Bak peptide interaction by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200966(CHEMBL220296 | ethyl2-amino-4-(1-cyano-2-ethoxy-2-...)
Affinity DataKi:  5.31E+5nMAssay Description:Binding affinity to Bcl2 by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200966(CHEMBL220296 | ethyl2-amino-4-(1-cyano-2-ethoxy-2-...)
Affinity DataKi:  5.70E+5nMAssay Description:Binding affinity to BclXL by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200965(2-Amino-6-bromo-4-(cyano-ethoxycarbonyl-methyl)-4H...)
Affinity DataKi:  6.60E+5nMAssay Description:Inhibition of recombinant His6-tagged Bcl-XL expressed in Escherichia coli BL21 (DE3) and Flu-Bak peptide interaction by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200966(CHEMBL220296 | ethyl2-amino-4-(1-cyano-2-ethoxy-2-...)
Affinity DataKi:  6.97E+5nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297393(CHEMBL561602 | Ethyl 2-Amino-6-(3',5'-dimethoxyphe...)
Affinity DataKi:  1.24E+6nMAssay Description:Inhibition of recombinant His6-tagged Bcl-XL expressed in Escherichia coli BL21 (DE3) and Flu-Bak peptide interaction by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297393(CHEMBL561602 | Ethyl 2-Amino-6-(3',5'-dimethoxyphe...)
Affinity DataKi:  4.20E+7nMAssay Description:Inhibition of recombinant His6-tagged MCL1 (171-326) expressed in Escherichia coli BL21 (DE3) and Flu-Bak peptide interaction by fluorescence polariz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed