TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Basilea Pharmaceutica
US Patent
Basilea Pharmaceutica
US Patent
Affinity DataIC50: 0.100nMAssay Description:PDEs specifically hydrolyze cAMP and/or cGMP and release the product AMP and/or GMP. The potency of PDE inhibition by test compounds is determined wi...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Basilea Pharmaceutica
US Patent
Basilea Pharmaceutica
US Patent
Affinity DataIC50: 30nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Basilea Pharmaceutica
US Patent
Basilea Pharmaceutica
US Patent
Affinity DataIC50: 31nMAssay Description:PDEs specifically hydrolyze cAMP and/or cGMP and release the product AMP and/or GMP. The potency of PDE inhibition by test compounds is determined wi...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Basilea Pharmaceutica
US Patent
Basilea Pharmaceutica
US Patent
Affinity DataIC50: 35nMAssay Description:PDEs specifically hydrolyze cAMP and/or cGMP and release the product AMP and/or GMP. The potency of PDE inhibition by test compounds is determined wi...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Basilea Pharmaceutica
US Patent
Basilea Pharmaceutica
US Patent
Affinity DataIC50: 43nMAssay Description:PDEs specifically hydrolyze cAMP and/or cGMP and release the product AMP and/or GMP. The potency of PDE inhibition by test compounds is determined wi...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Basilea Pharmaceutica
US Patent
Basilea Pharmaceutica
US Patent
Affinity DataIC50: 71nMAssay Description:PDEs specifically hydrolyze cAMP and/or cGMP and release the product AMP and/or GMP. The potency of PDE inhibition by test compounds is determined wi...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Basilea Pharmaceutica
US Patent
Basilea Pharmaceutica
US Patent
Affinity DataIC50: 200nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Basilea Pharmaceutica
US Patent
Basilea Pharmaceutica
US Patent
Affinity DataIC50: 230nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Basilea Pharmaceutica
US Patent
Basilea Pharmaceutica
US Patent
Affinity DataIC50: 300nMAssay Description:PDEs specifically hydrolyze cAMP and/or cGMP and release the product AMP and/or GMP. The potency of PDE inhibition by test compounds is determined wi...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Basilea Pharmaceutica
US Patent
Basilea Pharmaceutica
US Patent
Affinity DataIC50: 630nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Basilea Pharmaceutica
US Patent
Basilea Pharmaceutica
US Patent
Affinity DataIC50: 876nMAssay Description:PDEs specifically hydrolyze cAMP and/or cGMP and release the product AMP and/or GMP. The potency of PDE inhibition by test compounds is determined wi...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Basilea Pharmaceutica
US Patent
Basilea Pharmaceutica
US Patent
Affinity DataIC50: 880nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: >2.10E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: >2.20E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: >2.20E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: >2.30E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: >2.40E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: >2.70E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: >2.80E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: >4.20E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 8.13E+5nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair