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Found 141 with Last Name = 'duggan' and Initial = 'pj'
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50461301(CHEMBL4227475)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50561000(CHEMBL1551597)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human T type calcium channel Cav3.2 expressed in HEK-293T cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Csiro Manufacturing Flagship (Biomedical)

Curated by ChEMBL
LigandPNGBDBM50022087(CHEBI:6694 | CHEMBL3298066)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of amyloid beta1-42 (unknown origin) aggregation assessed as amyloid fibril formation tested after 17 hrs by thioflavin T fluorescence met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Csiro Manufacturing Flagship (Biomedical)

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of amyloid beta1-42 (unknown origin) aggregation assessed as amyloid fibril formation tested after 17 hrs by thioflavin T fluorescence met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Csiro Manufacturing Flagship (Biomedical)

Curated by ChEMBL
LigandPNGBDBM50022088(CHEMBL3297746)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of amyloid beta1-42 (unknown origin) aggregation assessed as amyloid fibril formation tested after 17 hrs by thioflavin T fluorescence met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Csiro Manufacturing Flagship (Biomedical)

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of amyloid beta1-42 (unknown origin) aggregation assessed as amyloid fibril formation tested after 17 hrs by thioflavin T fluorescence met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50561000(CHEMBL1551597)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human N type calcium channel Cav2.2 endogenously expressed in SH-SY5Y cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50461301(CHEMBL4227475)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM77970(3-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM112774(US8629135, SW-01)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50101973(BA-34276 [As Hydrochloride] | CHEBI:6690 | Maproti...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM112777(NORTRIPTYLINE | US8629135, SW-02)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50240410(10,11-dihydro-N,N,beta-trimethyl-5H-dibenz[b,f]aze...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50020712(10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50176062(3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50017696((2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiaz...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM112780(US8629135, SW-07)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50561005(CHEMBL4741422)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human T type calcium channel Cav3.2 expressed in HEK-293T cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50170636(2-[4-(3-Dibenzo[b,f]azepin-5-yl-propyl)-piperazin-...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50101813(CHEBI:31399 | Cilnidipine)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human T type calcium channel Cav3.2 expressed in HEK-293T cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50101813(CHEBI:31399 | Cilnidipine)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50101813(CHEBI:31399 | Cilnidipine)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of human N type calcium channel Cav2.2 endogenously expressed in SH-SY5Y cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM22870(13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50561001(CHEMBL4800369)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of human Cav2.2 expressed in HEK293 cells by whole cell patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50561010(CHEMBL4794579)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of human N type calcium channel Cav2.2 endogenously expressed in SH-SY5Y cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50461289(MK-6721 | NMED-160 | NP-118809 | Z-160 | Z160)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50461288(CHEMBL4226804)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50561002(CHEMBL4759180)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human T type calcium channel Cav3.2 expressed in HEK-293T cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50461297(CHEMBL4226823)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50461290(CHEMBL4229218)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50561007(CHEMBL4742798)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human N type calcium channel Cav2.2 endogenously expressed in SH-SY5Y cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50461289(MK-6721 | NMED-160 | NP-118809 | Z-160 | Z160)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50461292(CHEMBL4226674)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50461282(CHEMBL4225603)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50561005(CHEMBL4741422)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of human N type calcium channel Cav2.2 endogenously expressed in SH-SY5Y cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50561010(CHEMBL4794579)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of human T type calcium channel Cav3.2 expressed in HEK-293T cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50461296(CHEMBL4227653)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50561004(CHEMBL4740547)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of human T type calcium channel Cav3.2 expressed in HEK-293T cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50461292(CHEMBL4226674)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50561007(CHEMBL4742798)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of human T type calcium channel Cav3.2 expressed in HEK-293T cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50561006(CHEMBL4764424)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of human T type calcium channel Cav3.2 expressed in HEK-293T cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50461278(CHEMBL4227740)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50561006(CHEMBL4764424)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of human N type calcium channel Cav2.2 endogenously expressed in SH-SY5Y cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50461276(CHEMBL4227450)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50461284(CHEMBL4226597)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50461276(CHEMBL4227450)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50461283(CHEMBL4225757)
Affinity DataIC50:  7.70E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50561009(CHEMBL4781385)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of human N type calcium channel Cav2.2 endogenously expressed in SH-SY5Y cells assessed as calcium influx by FRIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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