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Found 58 with Last Name = 'dumin' and Initial = 'j'
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215294(2-(N-(6-chloro-7-methyl-2,3-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215283(2-(N-(6,7-dichloro-2,3-dioxo-1,2,3,4-tetrahydroqui...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215284(2-(N-(7-chloro-6-methyl-2,3-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215282(CHEMBL429296 | N-(6-chloro-7-methyl-2,3-dioxo-1,2,...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215286(CHEMBL399275 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215286(CHEMBL399275 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215281(CHEMBL248443 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215287(CHEMBL247035 | N-(3-methoxybenzyl)-N-(6,7-dichloro...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215296(CHEMBL401849 | N-(7-chloro-6-methyl-2,3-dioxo-1,2,...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215285(CHEMBL400508 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215276(CHEMBL399519 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215281(CHEMBL248443 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215281(CHEMBL248443 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215279(CHEMBL248439 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  38nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215298(CHEMBL399075 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  39nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215297(CHEMBL247034 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215292(CHEMBL401100 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  41nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215280(CHEMBL248436 | N-(3-fluorobenzyl)-N-(6,7-dichloro-...)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215278(CHEMBL248446 | N-(6-chloro-7-ethyl-2,3-dioxo-1,2,3...)
Affinity DataIC50:  49nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215277(CHEMBL401253 | N-(7-chloro-6-ethyl-2,3-dioxo-1,2,3...)
Affinity DataIC50:  58nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215295(CHEMBL248438 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  59nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215291(CHEMBL248445 | N-(7-chloro-6-methyl-2,3-dioxo-1,2,...)
Affinity DataIC50:  74nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215288(CHEMBL248444 | N-(6-chloro-7-methyl-2,3-dioxo-1,2,...)
Affinity DataIC50:  77nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215276(CHEMBL399519 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  109nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215276(CHEMBL399519 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  109nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215290(CHEMBL399274 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  166nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215293(CHEMBL248442 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  209nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215286(CHEMBL399275 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  282nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215289(CHEMBL399700 | N-(7-chloro-2,3-dioxo-1,2,3,4-tetra...)
Affinity DataIC50:  728nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065241(CHEMBL2207044)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065108(CHEMBL3403818)
Affinity DataIC50:  1.60E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065197(CHEMBL3403824)
Affinity DataIC50:  1.90E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065109(CHEMBL3403819)
Affinity DataIC50:  2.70E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065193(CHEMBL3403820)
Affinity DataIC50:  2.70E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065193(CHEMBL3403820)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065194(CHEMBL3403821)
Affinity DataIC50:  3.20E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065203(CHEMBL2206994)
Affinity DataIC50:  3.90E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065194(CHEMBL3403821)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065109(CHEMBL3403819)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065197(CHEMBL3403824)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065196(CHEMBL3403823)
Affinity DataIC50:  7.70E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065198(CHEMBL3403825)
Affinity DataIC50:  7.80E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065199(CHEMBL3403826)
Affinity DataIC50:  1.10E+4nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065108(CHEMBL3403818)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065203(CHEMBL2206994)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065196(CHEMBL3403823)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065199(CHEMBL3403826)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065195(CHEMBL3403822)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065195(CHEMBL3403822)
Affinity DataIC50:  1.60E+4nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065200(CHEMBL3403827)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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