Affinity DataIC50: 0.400nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor measured using radioligand ([3H]spiperone) binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Compound was tested in vitro for its ability to displace radioligand (+)-[3H]-3-PPP from rat cortical sigma receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro affinity for rat striatal Dopamine receptor D2 labeled with [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]WB-4101 binding to rat cortical Alpha-1 adrenergic receptor in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro inhibitory concentration against radioligand [3H]spiperone binding to rat striatal dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Compound was tested in vitro for its affinity towards rat striatal Dopamine receptor D2 labeled with [3H]- spiperoneMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Ability to inhibit [3H]WB-4101 binding to rat cortical alpha-1-adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:In vitro affinity for rat striatal Dopamine receptor D2 labeled with [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Ability to inhibit [3H]WB-4101 binding to rat cortical alpha-1-adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:In vitro affinity for rat striatal Dopamine receptor D2 labeled with [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1 receptor was measured using radioligand ([3H]5-HT) binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Ability to inhibit [3H]WB-4101 binding to rat cortical alpha-1-adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Compound was tested in vitro for its affinity towards rat striatal Dopamine receptor D2 labeled with [3H]- spiperoneMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Ability to inhibit [3H]WB-4101 binding to rat cortical alpha-1-adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor was measured using radioligand ([3H]spiperone) binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Ability to inhibit [3H]WB-4101 binding to rat cortical alpha-1-adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor measured using radioligand ([3H]spiperone) binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Displacement of (+)-[3H]-3-PPP from rat cortical sigma siteMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]WB-4101 binding to rat cortical Alpha-1 adrenergic receptor in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:In vitro affinity for rat striatal Dopamine receptor D2 labeled with [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Displacement of (+)-[3H]-3-PPP from rat cortical sigma siteMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:In vitro affinity for rat striatal Dopamine receptor D2 labeled with [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Displacement of (+)-[3H]-3-PPP from rat cortical sigma siteMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Displacement of (+)-[3H]-3-PPP from rat cortical sigma siteMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibitory concentration against radioligand [3H]3-PPP binding to haloperidol-sensitive sigma binding site in whole guinea pig brainMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of [3H]WB-4101 binding to rat cortical Alpha-1 adrenergic receptor in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:In vitro affinity for rat striatal Dopamine receptor D2 labeled with [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibitory concentration against radioligand [3H]DTG binding to haloperidol-sensitive sigma binding site in whole guinea pig brainMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Ability to inhibit [3H]-spiperone binding to Dopamine receptor D2 in rat corpus striatumMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Ability to inhibit [3H]WB-4101 binding to rat cortical alpha-1-adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Ability to inhibit [3H]WB-4101 binding to rat cortical alpha-1-adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Ability to inhibit [3H]WB-4101 binding to rat cortical alpha-1-adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Ability to inhibit [3H]WB-4101 binding to rat cortical alpha-1-adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Ability to inhibit [3H]WB-4101 binding to rat cortical alpha-1-adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Compound was tested in vitro for its affinity towards rat striatal Dopamine receptor D2 labeled with [3H]- spiperoneMore data for this Ligand-Target Pair