Affinity DataKi: 0.0900nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor delta 1 in rat brain homogenates using [3H]DIDI as radioligandMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 0.330nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor delta 1 in rat brain homogenates using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
TargetEndothelin-1 receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 0.430nMAssay Description:Inhibition of [125I]-ET-1 binding to cloned human ET-A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.780nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor delta 1 in rat brain homogenates using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Inhibition of [3H]-SKF- 107260 binding to purified GPIIb/IIIa from human platelets reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 8.5nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
Affinity DataKi: 8.80nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
Affinity DataKi: 8.81nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor delta 1 in rat brain homogenates using [3H]DIDI as radioligandMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 9.30nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-2(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataKi: 11nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor delta 1 in rat brain homogenates using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 11.3nMAssay Description:Inhibition of [125I]-ET-1 binding to cloned human ET-A receptorMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 13.7nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor kappa 1 in rat brain homogenates using [3H]CI977 as radioligandMore data for this Ligand-Target Pair
TargetEndothelin receptor type B(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 14.7nMAssay Description:Inhibition of [125I]-ET-1 binding to cloned human ET-B receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 15nMAssay Description:Inhibition of [125I]-ET-1 binding to cloned human ET-A receptorMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetEndothelin receptor type B(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 24.3nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 24.5nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of 25-[26,27-3H]hydroxycholesterol from RORgammat receptor ligand binding domain (unknown origin) after 60 minsMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Compound was evaluated for the binding affinity towards mu opioid receptor in rat brain homogenates using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of 25-[26,27-3H]hydroxycholesterol from RORgammat receptor ligand binding domain (unknown origin) after 60 minsMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataKi: 39nMAssay Description:Compound was evaluated for the binding affinity towards mu opioid receptor in rat brain homogenates using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of 25-[26,27-3H]hydroxycholesterol from RORgammat receptor ligand binding domain (unknown origin) after 60 minsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Compound was evaluated for the displacement of labelled MK-499 from the cloned channel expressed in HEK cells (Ikrchannel)More data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 43nMAssay Description:Inhibition of [125I]-ET-1 binding to cloned human ET-A receptorMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 45nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Inhibition of [3H]-SKF- 107260 binding to purified GPIIb/IIIa from human platelets reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor kappa 1 in rat brain homogenates using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 65nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 77nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research And Development
Curated by ChEMBL
Affinity DataKi: 82nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair