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Found 170 with Last Name = 'ericsson' and Initial = 'am'
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  19nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155144(4-(3-Phenyl-1H-indol-2-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305013(3-(2-amino-7-(7-(benzo[b]thiophen-2-yl)-1H-indazol...)
Affinity DataIC50:  20nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  33nMAssay Description:Inhibition of IKK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305007(5-(3-aminopropyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305010(3-(2-amino-7-(7-(benzo[b]thiophen-2-yl)-1H-indazol...)
Affinity DataIC50:  37nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305014(3-(2-amino-7-(7-(benzo[b]thiophen-2-yl)-1H-indazol...)
Affinity DataIC50:  41nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  44nMAssay Description:Inhibition of CHK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  53nMAssay Description:Inhibition of pdk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305003(7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5H-p...)
Affinity DataIC50:  56nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155149(4-(3-Methyl-1H-indol-2-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155148((Z)-4-((4-(2-(diethylamino)ethyl)-3,5-dimethyl-1H-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C eta type(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  98nMAssay Description:Inhibition of PKCetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155151(4-((1-methyl-1H-indol-3-yl)methylene)-3-(pyrazin-2...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188272(7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...)
Affinity DataIC50:  103nMAssay Description:Inhibition of cKit by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  140nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155149(4-(3-Methyl-1H-indol-2-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50:  140nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188266(7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...)
Affinity DataIC50:  145nMAssay Description:Inhibition of cKit by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305000(CHEMBL600081 | N4-(3-(benzo[b]thiophen-2-yl)-1H-in...)
Affinity DataIC50:  160nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305001(CHEMBL592288 | N4-(3-(1H-pyrrol-2-yl)-1H-indazol-5...)
Affinity DataIC50:  160nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155146(2-[6-(2-Morpholin-4-yl-ethoxy)-1H-indol-3-ylmethyl...)
Affinity DataIC50:  160nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188272(7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...)
Affinity DataIC50:  169nMAssay Description:Inhibition of FLT4 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  170nMAssay Description:Inhibition of GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155147(2-[7-([1,4'']Bipiperidinyl-1''-carbonyl)-1H-indol-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50188266(7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...)
Affinity DataIC50:  180nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP/microtubule affinity-regulating kinase 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  210nMAssay Description:Inhibition of CTAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155148((Z)-4-((4-(2-(diethylamino)ethyl)-3,5-dimethyl-1H-...)
Affinity DataIC50:  210nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  230nMAssay Description:Inhibition of CDK5/P25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155151(4-((1-methyl-1H-indol-3-yl)methylene)-3-(pyrazin-2...)
Affinity DataIC50:  230nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305008(5-(4-aminobutyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  260nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155146(2-[6-(2-Morpholin-4-yl-ethoxy)-1H-indol-3-ylmethyl...)
Affinity DataIC50:  290nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50188272(7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...)
Affinity DataIC50:  293nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50304999(CHEMBL590834 | N4-(3-(naphthalen-2-yl)-1H-indazol-...)
Affinity DataIC50:  310nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  320nMAssay Description:Inhibition of CDC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  380nMAssay Description:Inhibition of PLK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  400nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50188283(6-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...)
Affinity DataIC50:  400nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155145(4-(1H-Indol-2-ylmethylene)-5-pyrazin-2-yl-2,4-dihy...)
Affinity DataIC50:  410nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  440nMAssay Description:Inhibition of DYRK1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  440nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155144(4-(3-Phenyl-1H-indol-2-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50:  470nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305016(7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5-is...)
Affinity DataIC50:  490nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50188281(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroi...)
Affinity DataIC50:  500nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  510nMAssay Description:Inhibition of PAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  530nMAssay Description:Inhibition of Ck1deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  570nMAssay Description:Inhibition of MST2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50188290(7-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-di...)
Affinity DataIC50:  600nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188272(7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...)
Affinity DataIC50:  601nMAssay Description:Inhibition of FLT1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human recombinant phospho-MK2 (36-400) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  690nMAssay Description:Inhibition of SGKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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