Affinity DataKi: 3.98nMAssay Description:Displacement of [3H]CP 55,940 from human CB1 receptor expressed in insect sf9 membranesMore data for this Ligand-Target Pair
Affinity DataKi: 6.31nMAssay Description:Displacement of [3H]CP 55,940 from human CB1 receptor expressed in insect sf9 membranesMore data for this Ligand-Target Pair
Affinity DataKi: 15.8nMAssay Description:Displacement of [3H]CP 55,940 from human CB2 receptor expressed in insect sf9 membranesMore data for this Ligand-Target Pair
Affinity DataKi: 19.9nMAssay Description:Displacement of [3H]CP 55,940 from human CB2 receptor expressed in insect sf9 membranesMore data for this Ligand-Target Pair
Affinity DataKi: 19.9nMAssay Description:Displacement of [3H]CP 55,940 from human CB1 receptor expressed in insect sf9 membranesMore data for this Ligand-Target Pair
Affinity DataKi: 19.9nMAssay Description:Displacement of [3H]CP 55,940 from human CB2 receptor expressed in insect sf9 membranesMore data for this Ligand-Target Pair
Affinity DataKi: 31.6nMAssay Description:Displacement of [3H]CP 55,940 from human CB1 receptor expressed in insect sf9 membranesMore data for this Ligand-Target Pair
Affinity DataKi: 50.1nMAssay Description:Displacement of [3H]CP 55,940 from human CB2 receptor expressed in insect sf9 membranesMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataKi: 1.26E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataKi: 5.01E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataKi: 6.31E+3nMAssay Description:Displacement of labeled-dofetilide from human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataKi: 6.31E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataKi: 2.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 0.158nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO-K1 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 0.501nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO-K1 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 1.26nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO-K1 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of mouse cathepsin SMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 2.51nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO-K1 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 3.16nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO-K1 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 3.16nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO-K1 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 3.16nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 3.98nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 5.01nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 5.01nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO-K1 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 7.94nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO-K1 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataIC50: 7.94nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO-K1 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair